ENSG00000168397


Homo sapiens

Features
Gene ID: ENSG00000168397
  
Biological name :ATG4B
  
Synonyms : ATG4B / autophagy related 4B cysteine peptidase / Q9Y4P1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.3
Gene start: 241637213
Gene end: 241673857
  
Corresponding Affymetrix probe sets: 204902_s_at (Human Genome U133 Plus 2.0 Array)   204903_x_at (Human Genome U133 Plus 2.0 Array)   212280_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000390597
Ensembl peptide - ENSP00000487133
Ensembl peptide - ENSP00000410526
Ensembl peptide - ENSP00000409895
Ensembl peptide - ENSP00000407389
Ensembl peptide - ENSP00000404783
Ensembl peptide - ENSP00000400050
Ensembl peptide - ENSP00000344960
Ensembl peptide - ENSP00000383582
Ensembl peptide - ENSP00000383583
Ensembl peptide - ENSP00000383964
Ensembl peptide - ENSP00000384259
Ensembl peptide - ENSP00000384661
NCBI entrez gene - 23192     See in Manteia.
OMIM - 611338
RefSeq - XM_017003640
RefSeq - XM_017003639
RefSeq - XM_017003638
RefSeq - XM_017003637
RefSeq - XM_005246996
RefSeq - XM_005246995
RefSeq - XM_005246993
RefSeq - NM_013325
RefSeq - XM_005246992
RefSeq - NM_178326
RefSeq Peptide - NP_037457
RefSeq Peptide - NP_847896
swissprot - Q9Y4P1
swissprot - C9JVD5
swissprot - H7C2A6
swissprot - H0Y2Y0
swissprot - F2Z2K8
swissprot - C9J1C1
swissprot - C9J3C0
swissprot - C9JIK8
swissprot - C9JQ72
Ensembl - ENSG00000168397
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atg4bENSDARG00000052104Danio rerio
 ATG4BENSGALG00000006298Gallus gallus
 Atg4bENSMUSG00000026280Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATG4A / Q8WYN0 / autophagy related 4A cysteine peptidaseENSG0000010184454
ATG4D / Q86TL0 / autophagy related 4D cysteine peptidaseENSG0000013073431
ATG4C / Q96DT6 / autophagy related 4C cysteine peptidaseENSG0000012570328


Protein motifs (from Interpro)
Interpro ID Name
 IPR005078  Peptidase C54
 IPR032916  Cysteine protease ATG4B, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IGI
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006501 C-terminal protein lipidation IBA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006612 protein targeting to membrane IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0044804 autophagy of nucleus IBA
 biological_processGO:0045732 positive regulation of protein catabolic process IEA
 biological_processGO:0051697 protein delipidation IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004175 endopeptidase activity IDA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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