ENSG00000125703


Homo sapiens

Features
Gene ID: ENSG00000125703
  
Biological name :ATG4C
  
Synonyms : ATG4C / autophagy related 4C cysteine peptidase / Q96DT6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p31.3
Gene start: 62784135
Gene end: 62865513
  
Corresponding Affymetrix probe sets: 228190_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396614
Ensembl peptide - ENSP00000360159
Ensembl peptide - ENSP00000360161
Ensembl peptide - ENSP00000391820
Ensembl peptide - ENSP00000322159
NCBI entrez gene - 84938     See in Manteia.
OMIM - 611339
RefSeq - XM_017002601
RefSeq - NM_032852
RefSeq - NM_178221
RefSeq - XM_005271288
RefSeq - XM_011542313
RefSeq - XM_017002600
RefSeq Peptide - NP_835739
RefSeq Peptide - NP_116241
swissprot - C9JC51
swissprot - H7BZW5
swissprot - Q96DT6
swissprot - A6NGQ4
Ensembl - ENSG00000125703
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atg4cENSDARG00000044373Danio rerio
 ATG4CENSGALG00000010985Gallus gallus
 Atg4cENSMUSG00000028550Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATG4D / Q86TL0 / autophagy related 4D cysteine peptidaseENSG0000013073446
ATG4A / Q8WYN0 / autophagy related 4A cysteine peptidaseENSG0000010184425
ATG4B / Q9Y4P1 / autophagy related 4B cysteine peptidaseENSG0000016839724


Protein motifs (from Interpro)
Interpro ID Name
 IPR005078  Peptidase C54
 IPR032915  Cysteine protease ATG4C


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IGI
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006501 C-terminal protein lipidation IBA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006612 protein targeting to membrane IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0044804 autophagy of nucleus IBA
 biological_processGO:0051697 protein delipidation IBA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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