ENSG00000102287


Homo sapiens

Features
Gene ID: ENSG00000102287
  
Biological name :GABRE
  
Synonyms : GABRE / gamma-aminobutyric acid type A receptor epsilon subunit / P78334
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q28
Gene start: 151953124
Gene end: 151974680
  
Corresponding Affymetrix probe sets: 204537_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359353
Ensembl peptide - ENSP00000389384
Ensembl peptide - ENSP00000397335
NCBI entrez gene - 2564     See in Manteia.
OMIM - 300093
RefSeq - XM_017029389
RefSeq - NM_004961
RefSeq - XM_017029386
RefSeq - XM_017029387
RefSeq Peptide - NP_004952
swissprot - F2Z2H5
swissprot - P78334
Ensembl - ENSG00000102287
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GabreENSMUSG00000031340Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GABRG3 / Q99928 / gamma-aminobutyric acid type A receptor gamma3 subunitENSG0000018225642
GABRG1 / Q8N1C3 / gamma-aminobutyric acid type A receptor gamma1 subunitENSG0000016328540
GABRG2 / P18507 / gamma-aminobutyric acid type A receptor gamma2 subunitENSG0000011332740
GABRA4 / P48169 / gamma-aminobutyric acid type A receptor alpha4 subunitENSG0000010915834
GABRA6 / Q16445 / gamma-aminobutyric acid type A receptor alpha6 subunitENSG0000014586334
GABRA1 / P14867 / gamma-aminobutyric acid type A receptor alpha1 subunitENSG0000002235532
GABRA5 / P31644 / gamma-aminobutyric acid type A receptor alpha5 subunitENSG0000018629732
GABRA3 / P34903 / gamma-aminobutyric acid type A receptor alpha3 subunitENSG0000001167732
GABRA2 / P47869 / gamma-aminobutyric acid type A receptor alpha2 subunitENSG0000015183432


Protein motifs (from Interpro)
Interpro ID Name
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR008099  Gamma-aminobutyric-acid A receptor epsilon subunit
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR036719  Neurotransmitter-gated ion-channel transmembrane domain superfamily
 IPR036734  Neurotransmitter-gated ion-channel ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 biological_processGO:2001226 negative regulation of chloride transport IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:1902711 GABA-A receptor complex IDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004890 GABA-A receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005254 chloride channel activity IEA
 molecular_functionGO:0022851 GABA-gated chloride ion channel activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr