ENSG00000182256


Homo sapiens

Features
Gene ID: ENSG00000182256
  
Biological name :GABRG3
  
Synonyms : GABRG3 / gamma-aminobutyric acid type A receptor gamma3 subunit / Q99928
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q12
Gene start: 26971282
Gene end: 27541991
  
Corresponding Affymetrix probe sets: 1555517_at (Human Genome U133 Plus 2.0 Array)   216895_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452244
Ensembl peptide - ENSP00000451862
Ensembl peptide - ENSP00000479113
Ensembl peptide - ENSP00000331912
Ensembl peptide - ENSP00000390708
Ensembl peptide - ENSP00000450976
NCBI entrez gene - 2567     See in Manteia.
OMIM - 600233
RefSeq - XM_017022060
RefSeq - NM_001270873
RefSeq - NM_033223
RefSeq - XM_011521430
RefSeq - XM_011521431
RefSeq - XM_017022058
RefSeq - XM_017022059
RefSeq Peptide - NP_150092
RefSeq Peptide - NP_001257802
swissprot - H0YJP1
swissprot - Q99928
swissprot - A0A0A0MR73
swissprot - H7BZQ0
swissprot - H0YJ81
Ensembl - ENSG00000182256
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039293Gallus gallus
 ENSGALG00000041042Gallus gallus
 Gabrg3ENSMUSG00000055026Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GABRG1 / Q8N1C3 / gamma-aminobutyric acid type A receptor gamma1 subunitENSG0000016328567
GABRG2 / P18507 / gamma-aminobutyric acid type A receptor gamma2 subunitENSG0000011332766
GABRE / P78334 / gamma-aminobutyric acid type A receptor epsilon subunitENSG0000010228746
GABRA6 / Q16445 / gamma-aminobutyric acid type A receptor alpha6 subunitENSG0000014586343
GABRA4 / P48169 / gamma-aminobutyric acid type A receptor alpha4 subunitENSG0000010915841
GABRA1 / P14867 / gamma-aminobutyric acid type A receptor alpha1 subunitENSG0000002235540
GABRA3 / P34903 / gamma-aminobutyric acid type A receptor alpha3 subunitENSG0000001167740
GABRA5 / P31644 / gamma-aminobutyric acid type A receptor alpha5 subunitENSG0000018629740
GABRA2 / P47869 / gamma-aminobutyric acid type A receptor alpha2 subunitENSG0000015183439


Protein motifs (from Interpro)
Interpro ID Name
 IPR005437  Gamma-aminobutyric-acid A receptor, gamma subunit
 IPR005440  Gamma-aminobutyric-acid A receptor, gamma 3 subunit
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR036719  Neurotransmitter-gated ion-channel transmembrane domain superfamily
 IPR036734  Neurotransmitter-gated ion-channel ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007214 gamma-aminobutyric acid signaling pathway IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004890 GABA-A receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005254 chloride channel activity IEA


Pathways (from Reactome)
Pathway description
Neurotransmitter receptors and postsynaptic signal transmission
GABA A receptor activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163288 GABRB1 / P18505 / gamma-aminobutyric acid type A receptor beta1 subunit  / complex
 ENSG00000166206 GABRB3 / P28472 / gamma-aminobutyric acid type A receptor beta3 subunit  / complex
 ENSG00000268089 GABRQ / Q9UN88 / gamma-aminobutyric acid type A receptor theta subunit  / complex
 ENSG00000145864 GABRB2 / P47870 / gamma-aminobutyric acid type A receptor beta2 subunit  / complex
 ENSG00000156642 NPTN / Q9Y639 / neuroplastin  / reaction / complex






 

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