ENSG00000163285


Homo sapiens

Features
Gene ID: ENSG00000163285
  
Biological name :GABRG1
  
Synonyms : GABRG1 / gamma-aminobutyric acid type A receptor gamma1 subunit / Q8N1C3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p12
Gene start: 46035769
Gene end: 46124081
  
Corresponding Affymetrix probe sets: 1552943_at (Human Genome U133 Plus 2.0 Array)   241805_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000295452
NCBI entrez gene - 2565     See in Manteia.
OMIM - 137166
RefSeq - NM_173536
RefSeq - XM_017007990
RefSeq Peptide - NP_775807
swissprot - Q8N1C3
Ensembl - ENSG00000163285
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gabrg1ENSDARG00000101995Danio rerio
 GABRG1ENSGALG00000020143Gallus gallus
 Gabrg1ENSMUSG00000001260Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GABRG2 / P18507 / gamma-aminobutyric acid type A receptor gamma2 subunitENSG0000011332774
GABRG3 / Q99928 / gamma-aminobutyric acid type A receptor gamma3 subunitENSG0000018225667
GABRA4 / P48169 / gamma-aminobutyric acid type A receptor alpha4 subunitENSG0000010915844
GABRA6 / Q16445 / gamma-aminobutyric acid type A receptor alpha6 subunitENSG0000014586343
GABRE / P78334 / gamma-aminobutyric acid type A receptor epsilon subunitENSG0000010228743
GABRA2 / P47869 / gamma-aminobutyric acid type A receptor alpha2 subunitENSG0000015183442
GABRA3 / P34903 / gamma-aminobutyric acid type A receptor alpha3 subunitENSG0000001167742
GABRA1 / P14867 / gamma-aminobutyric acid type A receptor alpha1 subunitENSG0000002235542
GABRA5 / P31644 / gamma-aminobutyric acid type A receptor alpha5 subunitENSG0000018629742


Protein motifs (from Interpro)
Interpro ID Name
 IPR005437  Gamma-aminobutyric-acid A receptor, gamma subunit
 IPR005438  Gamma-aminobutyric-acid A receptor, gamma 1 subunit
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR036719  Neurotransmitter-gated ion-channel transmembrane domain superfamily
 IPR036734  Neurotransmitter-gated ion-channel ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007214 gamma-aminobutyric acid signaling pathway IEA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0043235 receptor complex IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004890 GABA-A receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005254 chloride channel activity IEA
 molecular_functionGO:0050811 GABA receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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