ENSG00000104824


Homo sapiens

Features
Gene ID: ENSG00000104824
  
Biological name :HNRNPL
  
Synonyms : heterogeneous nuclear ribonucleoprotein L / HNRNPL / P14866
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.2
Gene start: 38836388
Gene end: 38852347
  
Corresponding Affymetrix probe sets: 202072_at (Human Genome U133 Plus 2.0 Array)   221860_at (Human Genome U133 Plus 2.0 Array)   35201_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000470231
Ensembl peptide - ENSP00000469913
Ensembl peptide - ENSP00000472150
Ensembl peptide - ENSP00000221419
Ensembl peptide - ENSP00000373401
Ensembl peptide - ENSP00000469349
NCBI entrez gene - 3191     See in Manteia.
OMIM - 603083
RefSeq - XM_011526889
RefSeq - NM_001005335
RefSeq - NM_001533
RefSeq - XM_011526886
RefSeq - XM_011526887
RefSeq - XM_011526888
RefSeq Peptide - NP_001005335
RefSeq Peptide - NP_001524
swissprot - M0QXS5
swissprot - M0QYL7
swissprot - M0R1W6
swissprot - P14866
swissprot - B4DVF8
Ensembl - ENSG00000104824
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hnrnplENSDARG00000035324Danio rerio
 hnrnpl2ENSDARG00000059303Danio rerio
 HnrnplENSMUSG00000015165Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WVV9 / HNRNPLL / heterogeneous nuclear ribonucleoprotein L likeENSG0000014388950
AC008982.1ENSG0000026808333
PTBP1 / P26599 / polypyrimidine tract binding protein 1ENSG0000001130425
PTBP3 / O95758 / polypyrimidine tract binding protein 3ENSG0000011931424
PTBP2 / Q9UKA9 / polypyrimidine tract binding protein 2ENSG0000011756924


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR006536  HnRNP-L/PTB
 IPR034816  hnRNP-L, RNA recognition motif 3
 IPR034817  hnRNP-L, RNA recognition motif 4
 IPR035005  hnRNP-L, RNA recognition motif 1
 IPR035008  hnRNP-L, RNA recognition motif 2
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IMP
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006396 RNA processing TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0016070 RNA metabolic process TAS
 biological_processGO:0034198 cellular response to amino acid starvation IEA
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IEA
 biological_processGO:1901652 response to peptide IEA
 biological_processGO:1902416 positive regulation of mRNA binding IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0035770 ribonucleoprotein granule IDA
 cellular_componentGO:0045120 pronucleus IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0097157 pre-mRNA intronic binding IDA
 molecular_functionGO:1990715 mRNA CDS binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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