ENSG00000117569


Homo sapiens

Features
Gene ID: ENSG00000117569
  
Biological name :PTBP2
  
Synonyms : polypyrimidine tract binding protein 2 / PTBP2 / Q9UKA9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p21.3
Gene start: 96721665
Gene end: 96823738
  
Corresponding Affymetrix probe sets: 1554614_a_at (Human Genome U133 Plus 2.0 Array)   218683_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359217
Ensembl peptide - ENSP00000412788
Ensembl peptide - ENSP00000477024
Ensembl peptide - ENSP00000359216
NCBI entrez gene - 58155     See in Manteia.
OMIM - 608449
RefSeq - NM_001300990
RefSeq - NM_021190
RefSeq - XM_017001951
RefSeq - NM_001300985
RefSeq - NM_001300986
RefSeq - NM_001300987
RefSeq - NM_001300988
RefSeq - NM_001300989
RefSeq - XM_011541874
RefSeq - XM_011541875
RefSeq - XM_011541876
RefSeq Peptide - NP_001287917
RefSeq Peptide - NP_001287919
RefSeq Peptide - NP_067013
RefSeq Peptide - NP_001287918
RefSeq Peptide - NP_001287914
RefSeq Peptide - NP_001287915
RefSeq Peptide - NP_001287916
swissprot - Q9UKA9
Ensembl - ENSG00000117569
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptbp2aENSDARG00000101947Danio rerio
 ptbp2bENSDARG00000015901Danio rerio
 PTBP2ENSGALG00000005552Gallus gallus
 Ptbp2ENSMUSG00000028134Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTBP1 / P26599 / polypyrimidine tract binding protein 1ENSG0000001130475
PTBP3 / O95758 / polypyrimidine tract binding protein 3ENSG0000011931470
HNRNPL / P14866 / heterogeneous nuclear ribonucleoprotein LENSG0000010482426
Q8WVV9 / HNRNPLL / heterogeneous nuclear ribonucleoprotein L likeENSG0000014388925
AC008982.1ENSG0000026808311


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR006536  HnRNP-L/PTB
 IPR034798  Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2
 IPR034799  PTBP2, RNA recognition motif 3
 IPR034800  PTBP2, RNA recognition motif 4
 IPR035002  PTBP2, RNA recognition motif 1
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006376 mRNA splice site selection IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0033119 negative regulation of RNA splicing IDA
 biological_processGO:2000177 regulation of neural precursor cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0036002 pre-mRNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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