ENSG00000104888


Homo sapiens

Features
Gene ID: ENSG00000104888
  
Biological name :SLC17A7
  
Synonyms : Q9P2U7 / SLC17A7 / solute carrier family 17 member 7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.33
Gene start: 49429401
Gene end: 49442360
  
Corresponding Affymetrix probe sets: 204229_at (Human Genome U133 Plus 2.0 Array)   204230_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000470338
Ensembl peptide - ENSP00000472086
Ensembl peptide - ENSP00000221485
NCBI entrez gene - 57030     See in Manteia.
OMIM - 605208
RefSeq - NM_020309
RefSeq Peptide - NP_064705
swissprot - M0R1S5
swissprot - Q9P2U7
Ensembl - ENSG00000104888
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc17a7aENSDARG00000016480Danio rerio
 slc17a7bENSDARG00000090106Danio rerio
 Q3TXX4ENSMUSG00000070570Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9P2U8 / SLC17A6 / solute carrier family 17 member 6ENSG0000009166477
Q8NDX2 / SLC17A8 / solute carrier family 17 member 8ENSG0000017952073
Q9NRA2 / SLC17A5 / solute carrier family 17 member 5ENSG0000011989933
O00624 / SLC17A2 / solute carrier family 17 member 2ENSG0000011233727
Q9Y2C5 / SLC17A4 / solute carrier family 17 member 4ENSG0000014603927
Q14916 / SLC17A1 / solute carrier family 17 member 1ENSG0000012456825
O00476 / SLC17A3 / solute carrier family 17 member 3ENSG0000012456425
Q9BYT1 / SLC17A9 / solute carrier family 17 member 9ENSG0000010119421


Protein motifs (from Interpro)
Interpro ID Name
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003407 neural retina development IEA
 biological_processGO:0006811 ion transport TAS
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006817 phosphate ion transport TAS
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007616 long-term memory IEA
 biological_processGO:0014047 glutamate secretion TAS
 biological_processGO:0015813 L-glutamate transmembrane transport IEA
 biological_processGO:0035249 synaptic transmission, glutamatergic IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0042137 sequestering of neurotransmitter IEA
 biological_processGO:0044341 sodium-dependent phosphate transport IEA
 biological_processGO:0051938 L-glutamate import IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0097401 synaptic vesicle lumen acidification IEA
 biological_processGO:0098700 neurotransmitter loading into synaptic vesicle IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030285 integral component of synaptic vesicle membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043229 intracellular organelle IEA
 cellular_componentGO:0044300 cerebellar mossy fiber IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0048786 presynaptic active zone IEA
 cellular_componentGO:0060076 excitatory synapse IEA
 cellular_componentGO:0060203 clathrin-sculpted glutamate transport vesicle membrane TAS
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0005313 L-glutamate transmembrane transporter activity TAS
 molecular_functionGO:0005315 inorganic phosphate transmembrane transporter activity IEA
 molecular_functionGO:0008068 extracellularly glutamate-gated chloride channel activity IEA
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0015319 sodium:inorganic phosphate symporter activity IDA
 molecular_functionGO:0015321 sodium-dependent phosphate transmembrane transporter activity IBA


Pathways (from Reactome)
Pathway description
Glutamate Neurotransmitter Release Cycle
Organic anion transporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105649 RAB3A / P20336 / RAB3A, member RAS oncogene family  / complex
 ENSG00000067715 SYT1 / P21579 / synaptotagmin 1  / complex
 ENSG00000220205 VAMP2 / P63027 / vesicle associated membrane protein 2  / complex






 

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