ENSG00000108599


Homo sapiens

Features
Gene ID: ENSG00000108599
  
Biological name :AKAP10
  
Synonyms : AKAP10 / A-kinase anchoring protein 10 / O43572
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p11.2
Gene start: 19904302
Gene end: 19978343
  
Corresponding Affymetrix probe sets: 205045_at (Human Genome U133 Plus 2.0 Array)   213396_s_at (Human Genome U133 Plus 2.0 Array)   236006_s_at (Human Genome U133 Plus 2.0 Array)   236007_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464079
Ensembl peptide - ENSP00000463398
Ensembl peptide - ENSP00000464294
Ensembl peptide - ENSP00000466329
Ensembl peptide - ENSP00000225737
Ensembl peptide - ENSP00000378907
Ensembl peptide - ENSP00000458637
Ensembl peptide - ENSP00000461040
Ensembl peptide - ENSP00000461793
NCBI entrez gene - 11216     See in Manteia.
OMIM - 604694
RefSeq - XM_017024071
RefSeq - NM_007202
RefSeq - XM_006721432
RefSeq Peptide - NP_009133
RefSeq Peptide - NP_001317081
swissprot - J3QL61
swissprot - J3QR74
swissprot - J3QRM7
swissprot - K7EM25
swissprot - A0A0S2Z4Z7
swissprot - O43572
swissprot - E7EMD6
swissprot - I3L479
swissprot - I3L177
swissprot - I3NI04
Ensembl - ENSG00000108599
  
Related genetic diseases (OMIM): 115080 - {Cardiac conduction defect, susceptibility to}, 115080
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akap10ENSDARG00000059549Danio rerio
 AKAP10ENSGALG00000004679Gallus gallus
 Akap10ENSMUSG00000047804Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR036305  RGS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0008104 protein localization TAS
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0051018 protein kinase A binding IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000005249 P31323 / PRKAR2B / protein kinase cAMP-dependent type II regulatory subunit beta  / reaction / complex
 ENSG00000114302 P13861 / PRKAR2A / protein kinase cAMP-dependent type II regulatory subunit alpha  / complex / reaction
 ENSG00000165059 P22612 / PRKACG / protein kinase cAMP-activated catalytic subunit gamma  / reaction / complex
 ENSG00000188191 P31321 / PRKAR1B / protein kinase cAMP-dependent type I regulatory subunit beta  / reaction / complex
 ENSG00000142875 P22694 / PRKACB / protein kinase cAMP-activated catalytic subunit beta  / reaction / complex
 ENSG00000072062 P17612 / PRKACA / protein kinase cAMP-activated catalytic subunit alpha  / reaction / complex
 ENSG00000108946 P10644 / PRKAR1A / protein kinase cAMP-dependent type I regulatory subunit alpha  / complex / reaction






 

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