ENSG00000111875


Homo sapiens

Features
Gene ID: ENSG00000111875
  
Biological name :ASF1A
  
Synonyms : anti-silencing function 1A histone chaperone / ASF1A / Q9Y294
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q22.31
Gene start: 118894220
Gene end: 118909167
  
Corresponding Affymetrix probe sets: 203427_at (Human Genome U133 Plus 2.0 Array)   203428_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000229595
NCBI entrez gene - 25842     See in Manteia.
OMIM - 609189
RefSeq - NM_014034
RefSeq Peptide - NP_054753
swissprot - Q9Y294
Ensembl - ENSG00000111875
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ASF1AENSGALG00000014887Gallus gallus
 Asf1aENSMUSG00000019857Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASF1B / Q9NVP2 / anti-silencing function 1B histone chaperoneENSG0000010501170


Protein motifs (from Interpro)
Interpro ID Name
 IPR006818  Histone chaperone ASF1-like
 IPR036747  Histone chaperone ASF1-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0006281 DNA repair IDA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006333 chromatin assembly or disassembly IEA
 biological_processGO:0006334 nucleosome assembly IDA
 biological_processGO:0006335 DNA replication-dependent nucleosome assembly IDA
 biological_processGO:0006336 DNA replication-independent nucleosome assembly IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0031936 negative regulation of chromatin silencing NAS
 biological_processGO:0042692 muscle cell differentiation IEA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042393 histone binding IDA


Pathways (from Reactome)
Pathway description
Formation of Senescence-Associated Heterochromatin Foci (SAHF)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000099991 CABIN1 / Q9Y6J0 / calcineurin binding protein 1  / complex / reaction
 ENSG00000100084 HIRA / P54198 / histone cell cycle regulator  / reaction / complex
 ENSG00000118900 UBN1 / Q9NPG3 / ubinuclein 1  / complex / reaction
 ENSG00000137309 HMGA1 / P17096 / high mobility group AT-hook 1  / complex / reaction
 ENSG00000189060 H1F0 / P07305 / H1 histone family member 0  / reaction
 ENSG00000149948 HMGA2 / P52926 / high mobility group AT-hook 2  / reaction / complex






 

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