ENSG00000115825


Homo sapiens

Features
Gene ID: ENSG00000115825
  
Biological name :PRKD3
  
Synonyms : O94806 / PRKD3 / protein kinase D3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p22.2
Gene start: 37250502
Gene end: 37324808
  
Corresponding Affymetrix probe sets: 1554910_at (Human Genome U133 Plus 2.0 Array)   211084_x_at (Human Genome U133 Plus 2.0 Array)   218236_s_at (Human Genome U133 Plus 2.0 Array)   222565_s_at (Human Genome U133 Plus 2.0 Array)   242549_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000234179
Ensembl peptide - ENSP00000398743
Ensembl peptide - ENSP00000399540
Ensembl peptide - ENSP00000401839
Ensembl peptide - ENSP00000368356
NCBI entrez gene - 23683     See in Manteia.
OMIM - 607077
RefSeq - XM_017003744
RefSeq - XM_005264237
RefSeq - XM_005264238
RefSeq - XM_017003741
RefSeq - XM_017003742
RefSeq - XM_017003743
RefSeq - NM_005813
RefSeq Peptide - NP_005804
swissprot - H0Y5M6
swissprot - H7C172
swissprot - C9JKP8
swissprot - O94806
Ensembl - ENSG00000115825
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prkd3ENSDARG00000079967Danio rerio
 PRKD3ENSGALG00000010612Gallus gallus
 Prkd3ENSMUSG00000024070Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRKD1 / Q15139 / protein kinase D1ENSG0000018430470
PRKD2 / Q9BZL6 / protein kinase D2ENSG0000010528764
LRRK2 / Q5S007 / leucine rich repeat kinase 2ENSG0000018890620
LRRK1 / Q38SD2 / leucine rich repeat kinase 1ENSG0000015423720


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR015727  Protein kinase C mu-related
 IPR017441  Protein kinase, ATP binding site
 IPR020454  Diacylglycerol/phorbol-ester binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0089700 protein kinase D signaling IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004697 protein kinase C activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000113163 Q9Y5P4 / COL4A3BP / collagen type IV alpha 3 binding protein  / reaction






 

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