ENSG00000116266


Homo sapiens

Features
Gene ID: ENSG00000116266
  
Biological name :STXBP3
  
Synonyms : O00186 / STXBP3 / syntaxin binding protein 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p13.3
Gene start: 108746674
Gene end: 108809526
  
Corresponding Affymetrix probe sets: 1560486_at (Human Genome U133 Plus 2.0 Array)   203310_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359025
NCBI entrez gene - 6814     See in Manteia.
OMIM - 608339
RefSeq - NM_007269
RefSeq Peptide - NP_009200
swissprot - O00186
Ensembl - ENSG00000116266
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stxbp3ENSDARG00000008142Danio rerio
 STXBP3ENSGALG00000002001Gallus gallus
 Q60770ENSMUSG00000027882Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P61764 / STXBP1 / syntaxin binding protein 1ENSG0000013685439
Q15833 / STXBP2 / syntaxin binding protein 2ENSG0000007694435


Protein motifs (from Interpro)
Interpro ID Name
 IPR001619  Sec1-like protein
 IPR036045  Sec1-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0006904 vesicle docking involved in exocytosis IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0022615 protein to membrane docking IEA
 biological_processGO:0030073 insulin secretion IEA
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0043312 neutrophil degranulation IEP
 biological_processGO:0045955 negative regulation of calcium ion-dependent exocytosis IMP
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:0070527 platelet aggregation IMP
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0031091 platelet alpha granule IDA
 cellular_componentGO:0042581 specific granule IDA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070820 tertiary granule IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017075 syntaxin-1 binding IEA
 molecular_functionGO:0019905 syntaxin binding IEA


Pathways (from Reactome)
Pathway description
Disinhibition of SNARE formation
Translocation of SLC2A4 (GLUT4) to the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000126583 PRKCG / P05129 / protein kinase C gamma  / reaction
 ENSG00000166501 PRKCB / P05771 / protein kinase C beta  / reaction
 ENSG00000154229 PRKCA / P17252 / protein kinase C alpha  / reaction
 ENSG00000103496 STX4 / Q12846 / syntaxin 4  / complex






 

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