ENSG00000117411


Homo sapiens

Features
Gene ID: ENSG00000117411
  
Biological name :B4GALT2
  
Synonyms : B4GALT2 / beta-1,4-galactosyltransferase 2 / O60909
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p34.1
Gene start: 43978943
Gene end: 43991170
  
Corresponding Affymetrix probe sets: 209413_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310696
Ensembl peptide - ENSP00000349293
Ensembl peptide - ENSP00000361399
Ensembl peptide - ENSP00000407468
NCBI entrez gene - 8704     See in Manteia.
OMIM - 604013
RefSeq - XM_017002717
RefSeq - NM_001005417
RefSeq - NM_003780
RefSeq - NM_030587
RefSeq - XM_017002716
RefSeq Peptide - NP_085076
RefSeq Peptide - NP_001005417
RefSeq Peptide - NP_003771
swissprot - O60909
Ensembl - ENSG00000117411
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 b4galt2ENSDARG00000077994Danio rerio
 B4GALT2ENSGALG00000010094Gallus gallus
 Q9Z2Y2ENSMUSG00000028541Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P15291 / B4GALT1 / beta-1,4-galactosyltransferase 1ENSG0000008606250
O60512 / B4GALT3 / beta-1,4-galactosyltransferase 3ENSG0000015885042
O60513 / B4GALT4 / beta-1,4-galactosyltransferase 4ENSG0000012157836
O43286 / B4GALT5 / beta-1,4-galactosyltransferase 5ENSG0000015847030
Q9UBX8 / B4GALT6 / beta-1,4-galactosyltransferase 6ENSG0000011827630
Q9UBV7 / B4GALT7 / beta-1,4-galactosyltransferase 7ENSG0000002784723


Protein motifs (from Interpro)
Interpro ID Name
 IPR003859  Beta-1,4-galactosyltransferase
 IPR027791  Galactosyltransferase, C-terminal
 IPR027995  Galactosyltransferase, N-terminal
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0018146 keratan sulfate biosynthetic process TAS
 biological_processGO:0021680 cerebellar Purkinje cell layer development IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity IEA
 molecular_functionGO:0003945 N-acetyllactosamine synthase activity IEA
 molecular_functionGO:0004461 lactose synthase activity IEA
 molecular_functionGO:0008378 galactosyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
N-Glycan antennae elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000117411 O60909 / B4GALT2 / beta-1,4-galactosyltransferase 2  / complex






 

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