ENSG00000158470


Homo sapiens

Features
Gene ID: ENSG00000158470
  
Biological name :B4GALT5
  
Synonyms : B4GALT5 / beta-1,4-galactosyltransferase 5 / O43286
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.13
Gene start: 49632945
Gene end: 49713878
  
Corresponding Affymetrix probe sets: 221484_at (Human Genome U133 Plus 2.0 Array)   221485_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360776
NCBI entrez gene - 9334     See in Manteia.
OMIM - 604016
RefSeq - NM_004776
RefSeq Peptide - NP_004767
swissprot - O43286
Ensembl - ENSG00000158470
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000008056Gallus gallus
 Q9JMK0ENSMUSG00000017929Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UBX8 / B4GALT6 / beta-1,4-galactosyltransferase 6ENSG0000011827671
P15291 / B4GALT1 / beta-1,4-galactosyltransferase 1ENSG0000008606235
O60512 / B4GALT3 / beta-1,4-galactosyltransferase 3ENSG0000015885034
O60909 / B4GALT2 / beta-1,4-galactosyltransferase 2ENSG0000011741131
O60513 / B4GALT4 / beta-1,4-galactosyltransferase 4ENSG0000012157829
Q9UBV7 / B4GALT7 / beta-1,4-galactosyltransferase 7ENSG0000002784724


Protein motifs (from Interpro)
Interpro ID Name
 IPR003859  Beta-1,4-galactosyltransferase
 IPR027791  Galactosyltransferase, C-terminal
 IPR027995  Galactosyltransferase, N-terminal
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0018146 keratan sulfate biosynthetic process TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity TAS
 molecular_functionGO:0008378 galactosyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
O-linked glycosylation of mucins
N-Glycan antennae elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000158470 O43286 / B4GALT5 / beta-1,4-galactosyltransferase 5  / complex






 

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