ENSG00000158850


Homo sapiens

Features
Gene ID: ENSG00000158850
  
Biological name :B4GALT3
  
Synonyms : B4GALT3 / beta-1,4-galactosyltransferase 3 / O60512
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.3
Gene start: 161171310
Gene end: 161177968
  
Corresponding Affymetrix probe sets: 210243_s_at (Human Genome U133 Plus 2.0 Array)   238312_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000320965
Ensembl peptide - ENSP00000356977
Ensembl peptide - ENSP00000480428
NCBI entrez gene - 8703     See in Manteia.
OMIM - 604014
RefSeq - XM_017002714
RefSeq - NM_001199873
RefSeq - NM_001199874
RefSeq - NM_003779
RefSeq - XM_005245566
RefSeq - XM_011510093
RefSeq Peptide - NP_001186802
RefSeq Peptide - NP_001186803
RefSeq Peptide - NP_003770
swissprot - O60512
Ensembl - ENSG00000158850
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 b4galt3ENSDARG00000062329Danio rerio
 Q91YY2ENSMUSG00000052423Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P15291 / B4GALT1 / beta-1,4-galactosyltransferase 1ENSG0000008606244
O60909 / B4GALT2 / beta-1,4-galactosyltransferase 2ENSG0000011741143
O60513 / B4GALT4 / beta-1,4-galactosyltransferase 4ENSG0000012157841
Q9UBX8 / B4GALT6 / beta-1,4-galactosyltransferase 6ENSG0000011827634
O43286 / B4GALT5 / beta-1,4-galactosyltransferase 5ENSG0000015847033
Q9UBV7 / B4GALT7 / beta-1,4-galactosyltransferase 7ENSG0000002784723


Protein motifs (from Interpro)
Interpro ID Name
 IPR003859  Beta-1,4-galactosyltransferase
 IPR027791  Galactosyltransferase, C-terminal
 IPR027995  Galactosyltransferase, N-terminal
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006682 galactosylceramide biosynthetic process IDA
 biological_processGO:0018146 keratan sulfate biosynthetic process TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity IEA
 molecular_functionGO:0003945 N-acetyllactosamine synthase activity IEA
 molecular_functionGO:0008378 galactosyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
N-Glycan antennae elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000158850 O60512 / B4GALT3 / beta-1,4-galactosyltransferase 3  / complex






 

1 s.

 
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