ENSG00000119547


Homo sapiens

Features
Gene ID: ENSG00000119547
  
Biological name :ONECUT2
  
Synonyms : O95948 / ONECUT2 / one cut homeobox 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q21.31
Gene start: 57435685
Gene end: 57491297
  
Corresponding Affymetrix probe sets: 207676_at (Human Genome U133 Plus 2.0 Array)   230271_at (Human Genome U133 Plus 2.0 Array)   233441_at (Human Genome U133 Plus 2.0 Array)   233446_at (Human Genome U133 Plus 2.0 Array)   239911_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419185
NCBI entrez gene - 9480     See in Manteia.
OMIM - 604894
RefSeq - NM_004852
RefSeq Peptide - NP_004843
swissprot - O95948
Ensembl - ENSG00000119547
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 onecut2ENSDARG00000090387Danio rerio
 ONECUT2ENSGALG00000035751Gallus gallus
 Q6XBJ3ENSMUSG00000045991Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UBC0 / ONECUT1 / one cut homeobox 1ENSG0000016985662
O60422 / ONECUT3 / one cut homeobox 3ENSG0000020592254
CUX1 / P39880 / Q13948 / cut like homeobox 1ENSG0000025792323
CUX2 / O14529 / cut like homeobox 2ENSG0000011124922


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003350  CUT domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0001952 regulation of cell-matrix adhesion IEA
 biological_processGO:0002064 epithelial cell development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IEA
 biological_processGO:0009887 animal organ morphogenesis TAS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0031018 endocrine pancreas development IEA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048935 peripheral nervous system neuron development IEA
 biological_processGO:0060271 cilium assembly IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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