ENSG00000169856


Homo sapiens

Features
Gene ID: ENSG00000169856
  
Biological name :ONECUT1
  
Synonyms : ONECUT1 / one cut homeobox 1 / Q9UBC0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q21.3
Gene start: 52756989
Gene end: 52791078
  
Corresponding Affymetrix probe sets: 210745_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453718
Ensembl peptide - ENSP00000302630
Ensembl peptide - ENSP00000476168
NCBI entrez gene - 3175     See in Manteia.
OMIM - 604164
RefSeq - NM_004498
RefSeq Peptide - NP_004489
swissprot - U3KQR8
swissprot - H0YMS2
swissprot - Q9UBC0
Ensembl - ENSG00000169856
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ONECUT1ENSGALG00000038618Gallus gallus
 O08755ENSMUSG00000043013Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O95948 / ONECUT2 / one cut homeobox 2ENSG0000011954767
O60422 / ONECUT3 / one cut homeobox 3ENSG0000020592257
CUX1 / P39880 / Q13948 / cut like homeobox 1ENSG0000025792326
CUX2 / O14529 / cut like homeobox 2ENSG0000011124924


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003350  CUT domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0001952 regulation of cell-matrix adhesion IEA
 biological_processGO:0002064 epithelial cell development IEA
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007492 endoderm development IEA
 biological_processGO:0009653 anatomical structure morphogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030183 B cell differentiation IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0031018 endocrine pancreas development IEA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048536 spleen development IEA
 biological_processGO:0048731 system development IBA
 biological_processGO:0060271 cilium assembly IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
Regulation of gene expression in early pancreatic precursor cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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