ENSG00000205922


Homo sapiens

Features
Gene ID: ENSG00000205922
  
Biological name :ONECUT3
  
Synonyms : O60422 / ONECUT3 / one cut homeobox 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 1752373
Gene end: 1780988
  
Corresponding Affymetrix probe sets: 1556962_at (Human Genome U133 Plus 2.0 Array)   234109_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000371786
NCBI entrez gene - 390874     See in Manteia.
OMIM - 611294
RefSeq - NM_001080488
RefSeq Peptide - NP_001073957
swissprot - O60422
Ensembl - ENSG00000205922
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 onecut3aENSDARG00000056395Danio rerio
 onecut3bENSDARG00000091059Danio rerio
 ONECUT3ENSGALG00000028081Gallus gallus
 Q8K557ENSMUSG00000045518Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O95948 / ONECUT2 / one cut homeobox 2ENSG0000011954755
Q9UBC0 / ONECUT1 / one cut homeobox 1ENSG0000016985654
CUX2 / O14529 / cut like homeobox 2ENSG0000011124924
CUX1 / P39880 / Q13948 / cut like homeobox 1ENSG0000025792322


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003350  CUT domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048731 system development IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
Regulation of gene expression in early pancreatic precursor cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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