ENSG00000120332


Homo sapiens

Features
Gene ID: ENSG00000120332
  
Biological name :TNN
  
Synonyms : Q9UQP3 / tenascin N / TNN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q25.1
Gene start: 175067858
Gene end: 175148066
  
Corresponding Affymetrix probe sets: 215271_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000239462
Ensembl peptide - ENSP00000481259
Ensembl peptide - ENSP00000480895
NCBI entrez gene - 63923     See in Manteia.
OMIM - 617472
RefSeq - XM_017002048
RefSeq - XM_017002049
RefSeq - NM_022093
RefSeq Peptide - NP_071376
swissprot - Q9UQP3
swissprot - A0A087WXT0
swissprot - A0A087WXC4
Ensembl - ENSG00000120332
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnnENSDARG00000024829Danio rerio
 TNNENSGALG00000004538Gallus gallus
 TnnENSMUSG00000026725Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNC / P24821 / tenascin CENSG0000004198236
TNR / Q92752 / tenascin RENSG0000011614736
FN1 / P02751 / fibronectin 1ENSG0000011541424
TNXB / P22105 / tenascin XBENSG0000016847716
FGA / P02671 / fibrinogen alpha chainENSG0000017156012
FGB / P02675 / fibrinogen beta chainENSG0000017156410
FGG / P02679 / fibrinogen gamma chainENSG000001715579
Q9Y5C1 / ANGPTL3 / angiopoietin like 3ENSG000001328558
Q86XS5 / ANGPTL5 / angiopoietin like 5ENSG000001871518
Q9BY76 / ANGPTL4 / angiopoietin like 4ENSG000001677727
FGL1 / Q08830 / fibrinogen like 1ENSG000001047607


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR002181  Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
 IPR003961  Fibronectin type III
 IPR013032  EGF-like, conserved site
 IPR013783  Immunoglobulin-like fold
 IPR014715  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
 IPR014716  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
 IPR020837  Fibrinogen, conserved site
 IPR036056  Fibrinogen-like, C-terminal
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002076 osteoblast development IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0033689 negative regulation of osteoblast proliferation IEA
 biological_processGO:0045668 negative regulation of osteoblast differentiation IEA
 biological_processGO:0070593 dendrite self-avoidance ISA
 biological_processGO:1905240 negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation IEA
 biological_processGO:2001223 negative regulation of neuron migration ISA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0097442 CA3 pyramidal cell dendrite IEA
 cellular_componentGO:1990026 hippocampal mossy fiber expansion IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000120332 TNN / Q9UQP3 / tenascin N  / complex






 

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