ENSG00000121281


Homo sapiens

Features
Gene ID: ENSG00000121281
  
Biological name :ADCY7
  
Synonyms : ADCY7 / adenylate cyclase 7 / P51828
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q12.1
Gene start: 50246137
Gene end: 50318135
  
Corresponding Affymetrix probe sets: 1554827_a_at (Human Genome U133 Plus 2.0 Array)   203741_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000460636
Ensembl peptide - ENSP00000457409
Ensembl peptide - ENSP00000460018
Ensembl peptide - ENSP00000254235
Ensembl peptide - ENSP00000378187
Ensembl peptide - ENSP00000437788
Ensembl peptide - ENSP00000454301
Ensembl peptide - ENSP00000455670
NCBI entrez gene - 113     See in Manteia.
OMIM - 600385
RefSeq - XM_017022899
RefSeq - XM_011522837
RefSeq - XM_011522838
RefSeq - XM_011522839
RefSeq - XM_011522840
RefSeq - XM_011522842
RefSeq - XM_017022895
RefSeq - XM_017022896
RefSeq - XM_017022897
RefSeq - XM_017022898
RefSeq - NM_001114
RefSeq - NM_001286057
RefSeq - XM_011522835
RefSeq - XM_011522836
RefSeq Peptide - NP_001105
RefSeq Peptide - NP_001272986
swissprot - H3BQ93
swissprot - I3L2Y1
swissprot - F5H699
swissprot - P51828
swissprot - F5H4D1
swissprot - I3L3Q5
swissprot - H3BMA5
Ensembl - ENSG00000121281
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adcy7ENSDARG00000060070Danio rerio
 ADCY7ENSGALG00000003837Gallus gallus
 Adcy7ENSMUSG00000031659Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADCY2 / Q08462 / adenylate cyclase 2ENSG0000007829555
ADCY4 / Q8NFM4 / adenylate cyclase 4ENSG0000012946751
ADCY5 / O95622 / adenylate cyclase 5ENSG0000017317537
ADCY6 / O43306 / adenylate cyclase 6ENSG0000017423337
ADCY1 / Q08828 / adenylate cyclase 1ENSG0000016474235
ADCY3 / O60266 / adenylate cyclase 3ENSG0000013803133
ADCY8 / P40145 / adenylate cyclase 8ENSG0000015589732
ADCY9 / O60503 / adenylate cyclase 9ENSG0000016210428


Protein motifs (from Interpro)
Interpro ID Name
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR009398  Adenylate cyclase, conserved domain
 IPR013833  Cytochrome c oxidase, subunit III, 4-helical bundle
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR029787  Nucleotide cyclase
 IPR030672  Adenylate cyclase
 IPR032628  Adenylate cyclase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003091 renal water homeostasis TAS
 biological_processGO:0006171 cAMP biosynthetic process IDA
 biological_processGO:0006182 cGMP biosynthetic process IBA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007190 activation of adenylate cyclase activity TAS
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway TAS
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0022904 respiratory electron transport chain IEA
 biological_processGO:0034199 activation of protein kinase A activity TAS
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0060135 maternal process involved in female pregnancy IEA
 biological_processGO:0071361 cellular response to ethanol IDA
 biological_processGO:0071377 cellular response to glucagon stimulus TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008074 guanylate cyclase complex, soluble IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004016 adenylate cyclase activity IDA
 molecular_functionGO:0004129 cytochrome-c oxidase activity IEA
 molecular_functionGO:0004383 guanylate cyclase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glucagon signaling in metabolic regulation
PKA activation
PKA activation in glucagon signalling
Adenylate cyclase activating pathway
Adenylate cyclase inhibitory pathway
G alpha (s) signalling events
G alpha (i) signalling events
G alpha (z) signalling events
Vasopressin regulates renal water homeostasis via Aquaporins
Hedgehog off state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr