ENSG00000121390


Homo sapiens

Features
Gene ID: ENSG00000121390
  
Biological name :PSPC1
  
Synonyms : paraspeckle component 1 / PSPC1 / Q8WXF1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q12.11
Gene start: 19674752
Gene end: 19783019
  
Corresponding Affymetrix probe sets: 218371_s_at (Human Genome U133 Plus 2.0 Array)   222611_s_at (Human Genome U133 Plus 2.0 Array)   222612_at (Human Genome U133 Plus 2.0 Array)   226574_at (Human Genome U133 Plus 2.0 Array)   226724_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436038
Ensembl peptide - ENSP00000435921
Ensembl peptide - ENSP00000481916
Ensembl peptide - ENSP00000488975
Ensembl peptide - ENSP00000343966
Ensembl peptide - ENSP00000393069
NCBI entrez gene - 55269     See in Manteia.
OMIM - 612408
RefSeq - XM_017020650
RefSeq - XM_006719844
RefSeq - XM_011535137
RefSeq - XM_011535139
RefSeq - XM_011535140
RefSeq - XM_011535141
RefSeq - XM_011535142
RefSeq - NM_001042414
RefSeq - NM_001354909
RefSeq Peptide - NP_001035879
RefSeq Peptide - NP_001341838
swissprot - A0A0U1RQF9
swissprot - X6RDA4
swissprot - A0A024RDP4
swissprot - Q8WXF1
Ensembl - ENSG00000121390
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pspc1ENSDARG00000006621Danio rerio
 PSPC1ENSGALG00000017142Gallus gallus
 Pspc1ENSMUSG00000021938Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NONO / Q15233 / non-POU domain containing octamer bindingENSG0000014714054
SFPQ / P23246 / splicing factor proline and glutamine richENSG0000011656054


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR012975  NOPS
 IPR034522  PSP1, RNA recognition motif 1
 IPR034523  PSP1, RNA recognition motif 2
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 biological_processGO:0002218 activation of innate immune response IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0042752 regulation of circadian rhythm ISS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0048511 rhythmic process IEA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0042382 paraspeckles IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0001047 core promoter binding ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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