ENSG00000128641


Homo sapiens

Features
Gene ID: ENSG00000128641
  
Biological name :MYO1B
  
Synonyms : MYO1B / myosin IB / O43795
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q32.3
Gene start: 191245185
Gene end: 191425389
  
Corresponding Affymetrix probe sets: 212364_at (Human Genome U133 Plus 2.0 Array)   212365_at (Human Genome U133 Plus 2.0 Array)   215074_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000341903
Ensembl peptide - ENSP00000489544
Ensembl peptide - ENSP00000408454
Ensembl peptide - ENSP00000401324
Ensembl peptide - ENSP00000399459
Ensembl peptide - ENSP00000388140
Ensembl peptide - ENSP00000387610
Ensembl peptide - ENSP00000376132
Ensembl peptide - ENSP00000376130
Ensembl peptide - ENSP00000306382
NCBI entrez gene - 4430     See in Manteia.
OMIM - 606537
RefSeq - XM_017004158
RefSeq - NM_001130158
RefSeq - NM_001161819
RefSeq - NM_001330237
RefSeq - NM_001330238
RefSeq - NM_012223
RefSeq - XM_005246572
RefSeq - XM_017004156
RefSeq - XM_017004157
RefSeq Peptide - NP_001317167
RefSeq Peptide - NP_036355
RefSeq Peptide - NP_001123630
RefSeq Peptide - NP_001155291
RefSeq Peptide - NP_001317166
swissprot - H7C2Y7
swissprot - C9K0I9
swissprot - C9JYW1
swissprot - C9JUP5
swissprot - B0I1S9
swissprot - A0A0U1RRI3
swissprot - O43795
swissprot - E9PDF6
swissprot - E7EQD9
Ensembl - ENSG00000128641
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myo1bENSDARG00000024694Danio rerio
 MYO1BENSGALG00000007712Gallus gallus
 Myo1bENSMUSG00000018417Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYO1A / Q9UBC5 / myosin IAENSG0000016686654
MYO1C / O00159 / myosin ICENSG0000019787940
MYO1H / Q8N1T3 / myosin IHENSG0000017452738
MYO1D / O94832 / myosin IDENSG0000017665836
MYO1E / Q12965 / myosin IEENSG0000015748334
MYO1G / B0I1T2 / myosin IGENSG0000013628634
MYO1F / O00160 / myosin IFENSG0000014234733
MYO15A / Q9UKN7 / myosin XVAENSG0000009153629
MYO15B / myosin XVBENSG0000026671422


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR010926  Class I myosin tail homology domain
 IPR011993  PH-like domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036072  Class I myosin, motor domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006892 post-Golgi vesicle-mediated transport IMP
 biological_processGO:0007015 actin filament organization IMP
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0030048 actin filament-based movement ISS
 biological_processGO:0051017 actin filament bundle assembly ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005884 actin filament IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005903 brush border ISS
 cellular_componentGO:0010008 endosome membrane IDA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0030175 filopodium ISS
 cellular_componentGO:0032588 trans-Golgi network membrane IDA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071944 cell periphery ISS
 molecular_functionGO:0000146 microfilament motor activity ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISS
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding ISS
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0030898 actin-dependent ATPase activity IEA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0051015 actin filament binding IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr