ENSG00000129204


Homo sapiens

Features
Gene ID: ENSG00000129204
  
Biological name :USP6
  
Synonyms : P35125 / ubiquitin specific peptidase 6 / USP6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.2
Gene start: 5116438
Gene end: 5175034
  
Corresponding Affymetrix probe sets: 1555063_at (Human Genome U133 Plus 2.0 Array)   1555065_x_at (Human Genome U133 Plus 2.0 Array)   206405_x_at (Human Genome U133 Plus 2.0 Array)   242242_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000250066
Ensembl peptide - ENSP00000460380
Ensembl peptide - ENSP00000461581
Ensembl peptide - ENSP00000461817
NCBI entrez gene - 9098     See in Manteia.
OMIM - 604334
RefSeq - XM_017025290
RefSeq - NM_001304284
RefSeq - NM_004505
RefSeq - XM_011524056
RefSeq - XM_011524057
RefSeq - XM_011524058
RefSeq - XM_011524059
RefSeq - XM_011524050
RefSeq - XM_011524051
RefSeq - XM_011524052
RefSeq - XM_011524053
RefSeq - XM_011524054
RefSeq - XM_011524055
RefSeq Peptide - NP_004496
RefSeq Peptide - NP_001291213
swissprot - P35125
swissprot - Q15635
Ensembl - ENSG00000129204
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp32ENSDARG00000061895Danio rerio
 ENSGALG00000005350Gallus gallus
 Usp32ENSMUSG00000000804Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP32 / Q8NFA0 / ubiquitin specific peptidase 32ENSG0000017083269
USP11 / P51784 / ubiquitin specific peptidase 11ENSG0000010222618
USP15 / Q9Y4E8 / ubiquitin specific peptidase 15ENSG0000013565518
USP4 / Q13107 / ubiquitin specific peptidase 4ENSG0000011431618
USP19 / O94966 / ubiquitin specific peptidase 19ENSG0000017204616
USP43 / Q70EL4 / ubiquitin specific peptidase 43ENSG0000015491412
USP31 / Q70CQ4 / ubiquitin specific peptidase 31ENSG0000010340412


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process NAS
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0016579 protein deubiquitination IDA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0060627 regulation of vesicle-mediated transport IDA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome TAS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0055037 recycling endosome IDA
 molecular_functionGO:0003676 nucleic acid binding TAS
 molecular_functionGO:0004197 cysteine-type endopeptidase activity TAS
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IDA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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