ENSG00000102226


Homo sapiens

Features
Gene ID: ENSG00000102226
  
Biological name :USP11
  
Synonyms : P51784 / ubiquitin specific peptidase 11 / USP11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p11.3
Gene start: 47232690
Gene end: 47248328
  
Corresponding Affymetrix probe sets: 208723_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366311
Ensembl peptide - ENSP00000218348
Ensembl peptide - ENSP00000366279
Ensembl peptide - ENSP00000366282
NCBI entrez gene - 8237     See in Manteia.
OMIM - 300050
RefSeq - XM_011543988
RefSeq - NM_004651
RefSeq - XM_005272674
RefSeq Peptide - NP_004642
swissprot - P51784
swissprot - Q5JXD3
swissprot - G5E9A6
swissprot - C9JBP8
Ensembl - ENSG00000102226
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp11ENSDARG00000076303Danio rerio
 Usp11ENSMUSG00000031066Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP4 / Q13107 / ubiquitin specific peptidase 4ENSG0000011431645
USP15 / Q9Y4E8 / ubiquitin specific peptidase 15ENSG0000013565545
USP32 / Q8NFA0 / ubiquitin specific peptidase 32ENSG0000017083232
USP19 / O94966 / ubiquitin specific peptidase 19ENSG0000017204629
USP6 / P35125 / ubiquitin specific peptidase 6ENSG0000012920426
USP31 / Q70CQ4 / ubiquitin specific peptidase 31ENSG0000010340419
USP43 / Q70EL4 / ubiquitin specific peptidase 43ENSG0000015491419


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR006615  Peptidase C19, ubiquitin-specific peptidase, DUSP domain
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028134  Ubiquitin carboxyl-terminal hydrolase USP4
 IPR028135  Ubiquitin-like domain, USP-type
 IPR028889  Ubiquitin specific protease domain
 IPR029346  Ubiquitin carboxyl-terminal hydrolase, C-terminal
 IPR035927  DUSP-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004197 cysteine-type endopeptidase activity TAS
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity TAS


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100906 NFKBIA / P25963 / NFKB inhibitor alpha  / complex






 

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