ENSG00000130584


Homo sapiens

Features
Gene ID: ENSG00000130584
  
Biological name :ZBTB46
  
Synonyms : Q86UZ6 / ZBTB46 / zinc finger and BTB domain containing 46
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.33
Gene start: 63743666
Gene end: 63831244
  
Corresponding Affymetrix probe sets: 227329_at (Human Genome U133 Plus 2.0 Array)   227358_at (Human Genome U133 Plus 2.0 Array)   243214_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000245663
Ensembl peptide - ENSP00000303102
Ensembl peptide - ENSP00000378536
NCBI entrez gene - 140685     See in Manteia.
OMIM - 614639
RefSeq - XM_011528548
RefSeq - NM_025224
RefSeq - XM_005260198
RefSeq - XM_006723700
RefSeq - XM_005260195
RefSeq - XM_005260196
RefSeq - XM_005260197
RefSeq Peptide - NP_079500
swissprot - Q86UZ6
Ensembl - ENSG00000130584
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb46ENSDARG00000078191Danio rerio
 ZBTB46ENSGALG00000006062Gallus gallus
 Q8BID6ENSMUSG00000027583Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96DT7 / ZBTB10 / zinc finger and BTB domain containing 10ENSG0000020518933
Q8NAP8 / ZBTB8B / zinc finger and BTB domain containing 8BENSG0000027327428
AL033529.1ENSG0000025455327
Q96BR9 / ZBTB8A / zinc finger and BTB domain containing 8AENSG0000016006223
HIC1 / Q14526 / HIC ZBTB transcriptional repressor 1ENSG0000017737419
Q99592 / ZBTB18 / zinc finger and BTB domain containing 18ENSG0000017945619
O95365 / ZBTB7A / zinc finger and BTB domain containing 7AENSG0000017895118
HIC2 / Q96JB3 / HIC ZBTB transcriptional repressor 2ENSG0000016963517
A1YPR0 / ZBTB7C / zinc finger and BTB domain containing 7CENSG0000018482816
O15156 / ZBTB7B / zinc finger and BTB domain containing 7BENSG0000016068516
B2RXF5 / ZBTB42 / zinc finger and BTB domain containing 42ENSG0000017962716
ZBTB5 / O15062 / zinc finger and BTB domain containing 5ENSG0000016879514
ZBTB3 / Q9H5J0 / zinc finger and BTB domain containing 3ENSG0000018567014


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030853 negative regulation of granulocyte differentiation IEA
 biological_processGO:0045650 negative regulation of macrophage differentiation IEA
 biological_processGO:0045656 negative regulation of monocyte differentiation IEA
 biological_processGO:2001199 negative regulation of dendritic cell differentiation IEA
 biological_processGO:2001200 positive regulation of dendritic cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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