ENSG00000160685


Homo sapiens

Features
Gene ID: ENSG00000160685
  
Biological name :ZBTB7B
  
Synonyms : O15156 / ZBTB7B / zinc finger and BTB domain containing 7B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.3
Gene start: 155002630
Gene end: 155018522
  
Corresponding Affymetrix probe sets: 205853_at (Human Genome U133 Plus 2.0 Array)   235145_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000292176
Ensembl peptide - ENSP00000357411
Ensembl peptide - ENSP00000406286
Ensembl peptide - ENSP00000438647
NCBI entrez gene - 51043     See in Manteia.
OMIM - 607646
RefSeq - XM_017001399
RefSeq - NM_001252406
RefSeq - NM_001256455
RefSeq - XM_006711359
RefSeq - XM_011509598
RefSeq - XM_011509599
RefSeq - XM_006711349
RefSeq - XM_006711353
RefSeq - XM_006711354
RefSeq - XM_006711356
RefSeq - XM_006711357
RefSeq - XM_006711358
RefSeq Peptide - NP_001243384
RefSeq Peptide - NP_001239335
swissprot - O15156
Ensembl - ENSG00000160685
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb7bENSDARG00000021891Danio rerio
 ENSGALG00000041484Gallus gallus
 Q64321ENSMUSG00000028042Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A1YPR0 / ZBTB7C / zinc finger and BTB domain containing 7CENSG0000018482839
O95365 / ZBTB7A / zinc finger and BTB domain containing 7AENSG0000017895134
HIC2 / Q96JB3 / HIC ZBTB transcriptional repressor 2ENSG0000016963521
HIC1 / Q14526 / HIC ZBTB transcriptional repressor 1ENSG0000017737421
Q99592 / ZBTB18 / zinc finger and BTB domain containing 18ENSG0000017945618
B2RXF5 / ZBTB42 / zinc finger and BTB domain containing 42ENSG0000017962717
Q86UZ6 / ZBTB46 / zinc finger and BTB domain containing 46ENSG0000013058416
ZBTB5 / O15062 / zinc finger and BTB domain containing 5ENSG0000016879516
ZBTB3 / Q9H5J0 / zinc finger and BTB domain containing 3ENSG0000018567015
Q96BR9 / ZBTB8A / zinc finger and BTB domain containing 8AENSG0000016006215
AL033529.1ENSG0000025455314
Q96DT7 / ZBTB10 / zinc finger and BTB domain containing 10ENSG0000020518914
Q8NAP8 / ZBTB8B / zinc finger and BTB domain containing 8BENSG0000027327414


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007398 ectoderm development TAS
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation IEA
 biological_processGO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:2000320 negative regulation of T-helper 17 cell differentiation IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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