ENSG00000169635


Homo sapiens

Features
Gene ID: ENSG00000169635
  
Biological name :HIC2
  
Synonyms : HIC2 / HIC ZBTB transcriptional repressor 2 / Q96JB3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q11.21
Gene start: 21417404
Gene end: 21451463
  
Corresponding Affymetrix probe sets: 212964_at (Human Genome U133 Plus 2.0 Array)   212965_at (Human Genome U133 Plus 2.0 Array)   212966_at (Human Genome U133 Plus 2.0 Array)   216911_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384889
Ensembl peptide - ENSP00000385319
Ensembl peptide - ENSP00000387757
NCBI entrez gene - 23119     See in Manteia.
OMIM - 607712
RefSeq - XM_017028669
RefSeq - NM_015094
RefSeq - XM_011530009
RefSeq - XM_011530010
RefSeq - XM_011530007
RefSeq - XM_011530008
RefSeq Peptide - NP_055909
swissprot - Q96JB3
Ensembl - ENSG00000169635
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hic1lENSDARG00000045660Danio rerio
 hic2ENSDARG00000100497Danio rerio
 HIC2ENSGALG00000033416Gallus gallus
 Hic2ENSMUSG00000050240Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HIC1 / Q14526 / HIC ZBTB transcriptional repressor 1ENSG0000017737447
Q99592 / ZBTB18 / zinc finger and BTB domain containing 18ENSG0000017945620
B2RXF5 / ZBTB42 / zinc finger and BTB domain containing 42ENSG0000017962719
O95365 / ZBTB7A / zinc finger and BTB domain containing 7AENSG0000017895119
O15156 / ZBTB7B / zinc finger and BTB domain containing 7BENSG0000016068519
ZBTB3 / Q9H5J0 / zinc finger and BTB domain containing 3ENSG0000018567018
ZBTB5 / O15062 / zinc finger and BTB domain containing 5ENSG0000016879517
Q96DT7 / ZBTB10 / zinc finger and BTB domain containing 10ENSG0000020518917
AL033529.1ENSG0000025455316
A1YPR0 / ZBTB7C / zinc finger and BTB domain containing 7CENSG0000018482816
Q8NAP8 / ZBTB8B / zinc finger and BTB domain containing 8BENSG0000027327416
Q86UZ6 / ZBTB46 / zinc finger and BTB domain containing 46ENSG0000013058416
Q96BR9 / ZBTB8A / zinc finger and BTB domain containing 8AENSG0000016006215


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated NAS
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding NAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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