ENSG00000178951


Homo sapiens

Features
Gene ID: ENSG00000178951
  
Biological name :ZBTB7A
  
Synonyms : O95365 / ZBTB7A / zinc finger and BTB domain containing 7A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 4044364
Gene end: 4066945
  
Corresponding Affymetrix probe sets: 213299_at (Human Genome U133 Plus 2.0 Array)   213303_x_at (Human Genome U133 Plus 2.0 Array)   219186_at (Human Genome U133 Plus 2.0 Array)   222082_at (Human Genome U133 Plus 2.0 Array)   226554_at (Human Genome U133 Plus 2.0 Array)   230709_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000323670
Ensembl peptide - ENSP00000471865
NCBI entrez gene - 51341     See in Manteia.
OMIM - 605878
RefSeq - XM_005259571
RefSeq - NM_001317990
RefSeq - NM_015898
RefSeq - XM_005259570
RefSeq Peptide - NP_001304919
RefSeq Peptide - NP_056982
swissprot - O95365
Ensembl - ENSG00000178951
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb7aENSDARG00000039899Danio rerio
 O93567ENSGALG00000025907Gallus gallus
 O88939ENSMUSG00000035011Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A1YPR0 / ZBTB7C / zinc finger and BTB domain containing 7CENSG0000018482837
O15156 / ZBTB7B / zinc finger and BTB domain containing 7BENSG0000016068534
HIC2 / Q96JB3 / HIC ZBTB transcriptional repressor 2ENSG0000016963520
HIC1 / Q14526 / HIC ZBTB transcriptional repressor 1ENSG0000017737420
ZBTB5 / O15062 / zinc finger and BTB domain containing 5ENSG0000016879519
Q99592 / ZBTB18 / zinc finger and BTB domain containing 18ENSG0000017945618
Q86UZ6 / ZBTB46 / zinc finger and BTB domain containing 46ENSG0000013058418
ZBTB3 / Q9H5J0 / zinc finger and BTB domain containing 3ENSG0000018567017
Q8NAP8 / ZBTB8B / zinc finger and BTB domain containing 8BENSG0000027327415
AL033529.1ENSG0000025455315
B2RXF5 / ZBTB42 / zinc finger and BTB domain containing 42ENSG0000017962715
Q96DT7 / ZBTB10 / zinc finger and BTB domain containing 10ENSG0000020518914
Q96BR9 / ZBTB8A / zinc finger and BTB domain containing 8AENSG0000016006214


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035035 histone acetyltransferase binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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