ENSG00000130943


Homo sapiens

Features
Gene ID: ENSG00000130943
  
Biological name :PKDREJ
  
Synonyms : PKDREJ / polycystin family receptor for egg jelly / Q9NTG1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.31
Gene start: 46255663
Gene end: 46263355
  
Corresponding Affymetrix probe sets: 220548_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000253255
NCBI entrez gene - 10343     See in Manteia.
OMIM - 604670
RefSeq - NM_006071
RefSeq Peptide - NP_006062
swissprot - Q9NTG1
Ensembl - ENSG00000130943
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039133Gallus gallus
 PkdrejENSMUSG00000052496Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PKD1 / P98161 / polycystin 1, transient receptor potential channel interactingENSG0000000871015
PKD1L1 / Q8TDX9 / polycystin 1 like 1, transient receptor potential channel interactingENSG0000015868315
PKD1L3 / Q7Z443 / polycystin 1 like 3, transient receptor potential channel interactingENSG0000027748114
PKD2 / Q13563 / polycystin 2, transient receptor potential cation channelENSG000001187626
PKD2L1 / Q9P0L9 / polycystin 2 like 1, transient receptor potential cation channelENSG000001075936
PKD2L2 / Q9NZM6 / polycystin 2 like 2, transient receptor potential cation channelENSG000000787955
PKD1L2 / Q7Z442 / polycystin 1 like 2 (gene/pseudogene)ENSG000001664732


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR001024  PLAT/LH2 domain
 IPR002859  PKD/REJ-like domain
 IPR003915  Polycystic kidney disease type 2 protein
 IPR013122  Polycystin cation channel, PKD1/PKD2
 IPR014010  REJ domain
 IPR036392  PLAT/LH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007340 acrosome reaction TAS
 biological_processGO:0050982 detection of mechanical stimulus IBA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005262 calcium channel activity IBA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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