ENSG00000133816


Homo sapiens

Features
Gene ID: ENSG00000133816
  
Biological name :MICAL2
  
Synonyms : MICAL2 / microtubule associated monooxygenase, calponin and LIM domain containing 2 / O94851 / Q6ZW33
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p15.3
Gene start: 12094008
Gene end: 12359144
  
Corresponding Affymetrix probe sets: 206275_s_at (Human Genome U133 Plus 2.0 Array)   212472_at (Human Genome U133 Plus 2.0 Array)   212473_s_at (Human Genome U133 Plus 2.0 Array)   236475_at (Human Genome U133 Plus 2.0 Array)   243611_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434209
Ensembl peptide - ENSP00000433509
Ensembl peptide - ENSP00000433818
Ensembl peptide - ENSP00000433965
Ensembl peptide - ENSP00000434957
Ensembl peptide - ENSP00000496085
Ensembl peptide - ENSP00000495880
Ensembl peptide - ENSP00000494982
Ensembl peptide - ENSP00000441689
Ensembl peptide - ENSP00000437229
Ensembl peptide - ENSP00000435270
Ensembl peptide - ENSP00000256186
Ensembl peptide - ENSP00000256194
Ensembl peptide - ENSP00000344894
Ensembl peptide - ENSP00000368932
Ensembl peptide - ENSP00000432324
Ensembl peptide - ENSP00000433357
NCBI entrez gene - 84953     See in Manteia.
NCBI entrez gene - 9645     See in Manteia.
OMIM - 612355
OMIM - 608881
RefSeq - NM_001346297
RefSeq - NM_001282663
RefSeq - NM_001282664
RefSeq - NM_001282665
RefSeq - NM_001282666
RefSeq - NM_001282667
RefSeq - NM_001346292
RefSeq - NM_001346293
RefSeq - NM_001346294
RefSeq - NM_001346295
RefSeq - NM_001346296
RefSeq - NM_014632
RefSeq - NM_032867
RefSeq - XM_011520490
RefSeq - XM_011520491
RefSeq - XM_017018589
RefSeq - XM_017018590
RefSeq - XM_017018591
RefSeq Peptide - NP_001333223
RefSeq Peptide - NP_001333224
RefSeq Peptide - NP_001333225
RefSeq Peptide - NP_001333226
RefSeq Peptide - NP_001333227
RefSeq Peptide - NP_001333228
RefSeq Peptide - NP_055447
RefSeq Peptide - NP_116256
RefSeq Peptide - NP_001269593
RefSeq Peptide - NP_001269594
RefSeq Peptide - NP_001269595
RefSeq Peptide - NP_001269596
RefSeq Peptide - NP_001269592
RefSeq Peptide - NP_001333221
RefSeq Peptide - NP_001333222
swissprot - E9PJB0
swissprot - Q6ZW33
swissprot - E9PRG5
swissprot - E9PRE0
swissprot - E9PNC3
swissprot - E9PL42
swissprot - E9PKW5
swissprot - E9PKI3
swissprot - O94851
Ensembl - ENSG00000133816
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F1RA39ENSDARG00000020395Danio rerio
 mical2aENSDARG00000075608Danio rerio
 MICAL2ENSGALG00000005540Gallus gallus
 Mical2ENSMUSG00000038244Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MICAL3 / Q7RTP6 / microtubule associated monooxygenase, calponin and LIM domain containing 3ENSG0000024315652
MICAL1 / Q8TDZ2 / microtubule associated monooxygenase, calponin and LIM domain containing 1ENSG0000013559633
Q5M775 / SPECC1 / sperm antigen with calponin homology and coiled-coil domains 1ENSG0000012848710
Q8N3D4 / EHBP1L1 / EH domain binding protein 1 like 1ENSG0000017344210
Q8IY33 / MICALL2 / MICAL like 2ENSG000001648779
EHBP1 / Q8NDI1 / EH domain binding protein 1ENSG000001155049
SMTN / P53814 / smoothelinENSG000001839639
Q69YQ0 / SPECC1L / sperm antigen with calponin homology and coiled-coil domains 1 likeENSG000001000149
SPECC1L-ADORA2A / SPECC1L-ADORA2A readthrough (NMD candidate)ENSG000002585559
Q8N3F8 / MICALL1 / MICAL like 1ENSG000001001399
Q2TAL5 / SMTNL2 / smoothelin like 2ENSG000001881766
A8MU46 / SMTNL1 / smoothelin like 1ENSG000002148725


Protein motifs (from Interpro)
Interpro ID Name
 IPR001715  Calponin homology domain
 IPR001781  Zinc finger, LIM-type
 IPR002938  FAD-binding domain
 IPR016103  ProQ/FinO domain
 IPR022735  bMERB domain
 IPR029939  MICAL2
 IPR036188  FAD/NAD(P)-binding domain superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping ISS
 biological_processGO:0007010 cytoskeleton organization IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007507 heart development ISS
 biological_processGO:0008150 biological_process ND
 biological_processGO:0010735 positive regulation of transcription via serum response element binding IMP
 biological_processGO:0019417 sulfur oxidation ISS
 biological_processGO:0030042 actin filament depolymerization ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0055114 oxidation-reduction process ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen ISS
 molecular_functionGO:0043914 NADPH:sulfur oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051019 mitogen-activated protein kinase binding ISS
 molecular_functionGO:0071949 FAD binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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