ENSG00000134744


Homo sapiens

Features
Gene ID: ENSG00000134744
  
Biological name :ZCCHC11
  
Synonyms : Q5TAX3 / ZCCHC11 / zinc finger CCHC-type containing 11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p32.3
Gene start: 52408282
Gene end: 52553487
  
Corresponding Affymetrix probe sets: 212704_at (Human Genome U133 Plus 2.0 Array)   217594_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434367
Ensembl peptide - ENSP00000433711
Ensembl peptide - ENSP00000434674
Ensembl peptide - ENSP00000437091
Ensembl peptide - ENSP00000436810
Ensembl peptide - ENSP00000435700
Ensembl peptide - ENSP00000435568
Ensembl peptide - ENSP00000435256
Ensembl peptide - ENSP00000257177
Ensembl peptide - ENSP00000348063
Ensembl peptide - ENSP00000360599
Ensembl peptide - ENSP00000432328
Ensembl peptide - ENSP00000432475
Ensembl peptide - ENSP00000433486
NCBI entrez gene - 23318     See in Manteia.
OMIM - 613692
RefSeq - XM_017000817
RefSeq - XM_011541099
RefSeq - XM_011541100
RefSeq - XM_011541101
RefSeq - XM_017000803
RefSeq - XM_017000804
RefSeq - XM_017000805
RefSeq - XM_017000806
RefSeq - XM_017000807
RefSeq - XM_017000808
RefSeq - XM_017000809
RefSeq - XM_017000810
RefSeq - XM_017000811
RefSeq - XM_017000812
RefSeq - XM_017000813
RefSeq - XM_017000814
RefSeq - XM_017000816
RefSeq - NM_001009881
RefSeq - NM_015269
RefSeq - XM_005270676
RefSeq - XM_005270678
RefSeq - XM_005270679
RefSeq - XM_005270680
RefSeq - XM_005270681
RefSeq - XM_005270682
RefSeq - XM_005270683
RefSeq - XM_006710498
RefSeq - XM_006710499
RefSeq - XM_006710500
RefSeq - XM_011541097
RefSeq - XM_011541098
RefSeq Peptide - NP_056084
RefSeq Peptide - NP_001009881
swissprot - E9PKY2
swissprot - E9PKX1
swissprot - E9PJN7
swissprot - H0YCX5
swissprot - H0YDJ1
swissprot - H0YDZ6
swissprot - H0YEE8
swissprot - H0YEY0
swissprot - H0YF28
swissprot - X6R5G7
swissprot - A0A0C4DFM7
swissprot - E9PRG2
swissprot - Q5TAX3
swissprot - E9PQS7
Ensembl - ENSG00000134744
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01065131.1ENSDARG00000101404Danio rerio
 zcchc11ENSDARG00000070271Danio rerio
 ZCCHC11ENSGALG00000010629Gallus gallus
 B2RX14ENSMUSG00000034610Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5VYS8 / ZCCHC6 / zinc finger CCHC-type containing 6ENSG0000008322337
TUT1 / Q9H6E5 / terminal uridylyl transferase 1, U6 snRNA-specificENSG000001490169
PAPD4 / Q6PIY7 / poly(A) RNA polymerase D4, non-canonicalENSG000001643298
MTPAP / Q9NVV4 / mitochondrial poly(A) polymeraseENSG000001079517
AP002990.1ENSG000002555086


Protein motifs (from Interpro)
Interpro ID Name
 IPR001878  Zinc finger, CCHC-type
 IPR002058  PAP/25A-associated
 IPR002934  Polymerase, nucleotidyl transferase domain
 IPR036875  Zinc finger, CCHC-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000289 nuclear-transcribed mRNA poly(A) tail shortening TAS
 biological_processGO:0001816 cytokine production IEA
 biological_processGO:0010586 miRNA metabolic process ISS
 biological_processGO:0010587 miRNA catabolic process IMP
 biological_processGO:0019827 stem cell population maintenance IMP
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0031054 pre-miRNA processing IMP
 biological_processGO:0031123 RNA 3"-end processing IDA
 biological_processGO:0031664 regulation of lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0070102 interleukin-6-mediated signaling pathway IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050265 RNA uridylyltransferase activity TAS


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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