ENSG00000135638


Homo sapiens

Features
Gene ID: ENSG00000135638
  
Biological name :EMX1
  
Synonyms : empty spiracles homeobox 1 / EMX1 / Q04741
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p13.2
Gene start: 72916260
Gene end: 72936071
  
Corresponding Affymetrix probe sets: 215264_at (Human Genome U133 Plus 2.0 Array)   215265_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258106
Ensembl peptide - ENSP00000482619
Ensembl peptide - ENSP00000446992
NCBI entrez gene - 2016     See in Manteia.
OMIM - 600034
RefSeq - NM_004097
RefSeq - XM_005264203
RefSeq Peptide - NP_004088
swissprot - A0A087WZF2
swissprot - Q04741
swissprot - F8W1B5
Ensembl - ENSG00000135638
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EMX1ENSGALG00000030516Gallus gallus
 Emx1ENSMUSG00000033726Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EMX2 / Q04743 / empty spiracles homeobox 2ENSG0000017037058
NOTO / A8MTQ0 / notochord homeoboxENSG0000021451322
VAX1 / Q5SQQ9 / ventral anterior homeobox 1ENSG0000014870419
VAX2 / Q9UIW0 / ventral anterior homeobox 2ENSG0000011603519
EN2 / P19622 / engrailed homeobox 2ENSG0000016477818
EN1 / Q05925 / engrailed homeobox 1ENSG0000016306417


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0021537 telencephalon development IEA
 biological_processGO:0021796 cerebral cortex regionalization IEA
 biological_processGO:0021895 cerebral cortex neuron differentiation IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0048854 brain morphogenesis IEA
 biological_processGO:0048872 homeostasis of number of cells IEA
 biological_processGO:0060019 radial glial cell differentiation IEA
 biological_processGO:0060563 neuroepithelial cell differentiation IEA
 biological_processGO:0070445 regulation of oligodendrocyte progenitor proliferation IEA
 biological_processGO:1990138 neuron projection extension IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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