ENSG00000139144


Homo sapiens

Features
Gene ID: ENSG00000139144
  
Biological name :PIK3C2G
  
Synonyms : O75747 / phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma / PIK3C2G
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p12.3
Gene start: 18247614
Gene end: 18648416
  
Corresponding Affymetrix probe sets: 215129_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445381
Ensembl peptide - ENSP00000443850
Ensembl peptide - ENSP00000479145
Ensembl peptide - ENSP00000266497
Ensembl peptide - ENSP00000404845
Ensembl peptide - ENSP00000441618
NCBI entrez gene - 5288     See in Manteia.
OMIM - 609001
RefSeq - XM_017019478
RefSeq - XM_017019470
RefSeq - XM_017019471
RefSeq - XM_017019472
RefSeq - XM_017019473
RefSeq - XM_017019474
RefSeq - XM_017019475
RefSeq - XM_017019476
RefSeq - XM_017019477
RefSeq - NM_001288772
RefSeq - NM_001288774
RefSeq - NM_004570
RefSeq - XM_011520696
RefSeq - XM_011520697
RefSeq - XM_011520700
RefSeq - XM_011520701
RefSeq Peptide - NP_004561
RefSeq Peptide - NP_001275701
RefSeq Peptide - NP_001275703
swissprot - F5GWG6
swissprot - A0A087WV31
swissprot - O75747
swissprot - F5H369
swissprot - F5H7Y7
Ensembl - ENSG00000139144
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pik3c2gENSDARG00000099803Danio rerio
 PIK3C2GENSGALG00000013117Gallus gallus
 Pik3c2gENSMUSG00000030228Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O00750 / PIK3C2B / phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 betaENSG0000013305635
O00443 / PIK3C2A / phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alphaENSG0000001140534
P48736 / PIK3CG / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gammaENSG0000010585117
P42336 / PIK3CA / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alphaENSG0000012187916
O00329 / PIK3CD / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit deltaENSG0000017160816
P42338 / PIK3CB / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit betaENSG0000005138215
PIK3C3 / Q8NEB9 / phosphatidylinositol 3-kinase catalytic subunit type 3ENSG0000007814212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000341  Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain
 IPR000403  Phosphatidylinositol 3-/4-kinase, catalytic domain
 IPR001263  Phosphoinositide 3-kinase, accessory (PIK) domain
 IPR001683  Phox homologous domain
 IPR002420  Phosphatidylinositol 3-kinase, C2 domain
 IPR011009  Protein kinase-like domain superfamily
 IPR015433  Phosphatidylinositol kinase
 IPR016024  Armadillo-type fold
 IPR018936  Phosphatidylinositol 3/4-kinase, conserved site
 IPR029071  Ubiquitin-like domain superfamily
 IPR035892  C2 domain superfamily
 IPR036871  PX domain superfamily
 IPR036940  Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006661 phosphatidylinositol biosynthetic process TAS
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0039694 viral RNA genome replication IMP
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005942 phosphatidylinositol 3-kinase complex IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity NAS
 molecular_functionGO:0016307 phosphatidylinositol phosphate kinase activity NAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0035004 phosphatidylinositol 3-kinase activity IEA
 molecular_functionGO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity IBA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
Synthesis of PIPs at the Golgi membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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