ENSG00000139154


Homo sapiens

Features
Gene ID: ENSG00000139154
  
Biological name :AEBP2
  
Synonyms : AE binding protein 2 / AEBP2 / Q6ZN18
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p12.3
Gene start: 19404045
Gene end: 19720801
  
Corresponding Affymetrix probe sets: 225889_at (Human Genome U133 Plus 2.0 Array)   235184_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445587
Ensembl peptide - ENSP00000266508
Ensembl peptide - ENSP00000354267
Ensembl peptide - ENSP00000381715
Ensembl peptide - ENSP00000381840
Ensembl peptide - ENSP00000437983
Ensembl peptide - ENSP00000444255
NCBI entrez gene - 121536     See in Manteia.
RefSeq - XM_017018806
RefSeq - NM_001114176
RefSeq - NM_001267043
RefSeq - NM_153207
RefSeq - XM_006719031
RefSeq Peptide - NP_001253972
RefSeq Peptide - NP_001107648
RefSeq Peptide - NP_694939
swissprot - H0YH08
swissprot - H7BYT4
swissprot - G5EA50
swissprot - F5GZR7
swissprot - Q6ZN18
Ensembl - ENSG00000139154
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aebp2ENSDARG00000006038Danio rerio
 AEBP2ENSGALG00000038026Gallus gallus
 Aebp2ENSMUSG00000030232Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045814 negative regulation of gene expression, epigenetic TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0035098 ESC/E(Z) complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA
PKMTs methylate histone lysines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000074266 EED / O75530 / embryonic ectoderm development  / complex
 ENSG00000178691 SUZ12 / Q15022 / SUZ12 polycomb repressive complex 2 subunit  / complex
 ENSG00000106462 EZH2 / Q15910 / enhancer of zeste 2 polycomb repressive complex 2 subunit  / complex
 ENSG00000102054 RBBP7 / Q16576 / RB binding protein 7, chromatin remodeling factor  / complex
 ENSG00000162521 RBBP4 / Q09028 / RB binding protein 4, chromatin remodeling factor  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr