ENSG00000140829


Homo sapiens

Features
Gene ID: ENSG00000140829
  
Biological name :DHX38
  
Synonyms : DEAH-box helicase 38 / DHX38 / Q92620
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.2
Gene start: 72093562
Gene end: 72112912
  
Corresponding Affymetrix probe sets: 209178_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000462965
Ensembl peptide - ENSP00000462149
Ensembl peptide - ENSP00000462397
Ensembl peptide - ENSP00000268482
Ensembl peptide - ENSP00000454521
Ensembl peptide - ENSP00000455939
Ensembl peptide - ENSP00000457887
NCBI entrez gene - 9785     See in Manteia.
OMIM - 605584
RefSeq - XM_017023913
RefSeq - NM_014003
RefSeq - XM_005256269
RefSeq - XM_011523484
RefSeq - XM_011523485
RefSeq Peptide - NP_054722
swissprot - H3BMS7
swissprot - Q92620
swissprot - H3BQT9
swissprot - H3BV01
swissprot - J3KRT1
swissprot - J3KTG2
swissprot - J3KSA8
Ensembl - ENSG00000140829
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhx38ENSDARG00000100013Danio rerio
 DHX38ENSGALG00000000787Gallus gallus
 Dhx38ENSMUSG00000037993Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DHX8 / Q14562 / DEAH-box helicase 8ENSG0000006759637
DHX16 / O60231 / DEAH-box helicase 16ENSG0000020456032
DHX15 / O43143 / DEAH-box helicase 15ENSG0000010960626
DHX35 / Q9H5Z1 / DEAH-box helicase 35ENSG0000010145224
DHX33 / Q9H6R0 / DEAH-box helicase 33ENSG0000000510024
DHX40 / Q8IX18 / DEAH-box helicase 40ENSG0000010840623
DHX34 / Q14147 / DExH-box helicase 34ENSG0000013481521


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR007502  Helicase-associated domain
 IPR011545  DEAD/DEAH box helicase domain
 IPR011709  Domain of unknown function DUF1605
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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