ENSG00000109606


Homo sapiens

Features
Gene ID: ENSG00000109606
  
Biological name :DHX15
  
Synonyms : DEAH-box helicase 15 / DHX15 / O43143
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p15.2
Gene start: 24517441
Gene end: 24584550
  
Corresponding Affymetrix probe sets: 201385_at (Human Genome U133 Plus 2.0 Array)   201386_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000336741
NCBI entrez gene - 1665     See in Manteia.
OMIM - 603403
RefSeq - NM_001358
RefSeq Peptide - NP_001349
swissprot - O43143
Ensembl - ENSG00000109606
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhx15ENSDARG00000015392Danio rerio
 DHX15ENSGALG00000014395Gallus gallus
 Dhx15ENSMUSG00000029169Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DHX8 / Q14562 / DEAH-box helicase 8ENSG0000006759647
DHX16 / O60231 / DEAH-box helicase 16ENSG0000020456045
DHX38 / Q92620 / DEAH-box helicase 38ENSG0000014082940
DHX35 / Q9H5Z1 / DEAH-box helicase 35ENSG0000010145237
DHX33 / Q9H6R0 / DEAH-box helicase 33ENSG0000000510035
DHX40 / Q8IX18 / DEAH-box helicase 40ENSG0000010840634
DHX34 / Q14147 / DExH-box helicase 34ENSG0000013481531


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR007502  Helicase-associated domain
 IPR011545  DEAD/DEAH box helicase domain
 IPR011709  Domain of unknown function DUF1605
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0008380 RNA splicing IC
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0043279 response to alkaloid IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005689 U12-type spliceosomal complex IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0071008 U2-type post-mRNA release spliceosomal complex IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003724 RNA helicase activity TAS
 molecular_functionGO:0003725 double-stranded RNA binding IDA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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