ENSG00000005100


Homo sapiens

Features
Gene ID: ENSG00000005100
  
Biological name :DHX33
  
Synonyms : DEAH-box helicase 33 / DHX33 / Q9H6R0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.2
Gene start: 5440912
Gene end: 5469060
  
Corresponding Affymetrix probe sets: 222875_at (Human Genome U133 Plus 2.0 Array)   226262_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000225296
Ensembl peptide - ENSP00000413779
Ensembl peptide - ENSP00000458203
Ensembl peptide - ENSP00000458925
NCBI entrez gene - 56919     See in Manteia.
OMIM - 614405
RefSeq - XM_017024877
RefSeq - NM_001199699
RefSeq - NM_020162
RefSeq Peptide - NP_001186628
RefSeq Peptide - NP_064547
swissprot - I3L0M5
swissprot - Q05BE5
swissprot - I3L1L6
swissprot - Q9H6R0
Ensembl - ENSG00000005100
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhx33ENSDARG00000051785Danio rerio
 DHX33ENSGALG00000001630Gallus gallus
 Dhx33ENSMUSG00000040620Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DHX8 / Q14562 / DEAH-box helicase 8ENSG0000006759644
DHX16 / O60231 / DEAH-box helicase 16ENSG0000020456043
DHX38 / Q92620 / DEAH-box helicase 38ENSG0000014082941
DHX35 / Q9H5Z1 / DEAH-box helicase 35ENSG0000010145241
DHX15 / O43143 / DEAH-box helicase 15ENSG0000010960639
DHX40 / Q8IX18 / DEAH-box helicase 40ENSG0000010840635
DHX34 / Q14147 / DExH-box helicase 34ENSG0000013481534


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR007502  Helicase-associated domain
 IPR011545  DEAD/DEAH box helicase domain
 IPR011709  Domain of unknown function DUF1605
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006396 RNA processing IBA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0032481 positive regulation of type I interferon production IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0045943 positive regulation of transcription by RNA polymerase I IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:1900227 positive regulation of NLRP3 inflammasome complex assembly IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0072559 NLRP3 inflammasome complex IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000182 rDNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0033613 activating transcription factor binding IEA
 molecular_functionGO:0043023 ribosomal large subunit binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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