ENSG00000141198


Homo sapiens

Features
Gene ID: ENSG00000141198
  
Biological name :TOM1L1
  
Synonyms : O75674 / target of myb1 like 1 membrane trafficking protein / TOM1L1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q22
Gene start: 54899387
Gene end: 54961956
  
Corresponding Affymetrix probe sets: 204485_s_at (Human Genome U133 Plus 2.0 Array)   240261_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467227
Ensembl peptide - ENSP00000461396
Ensembl peptide - ENSP00000461876
Ensembl peptide - ENSP00000343901
Ensembl peptide - ENSP00000408958
Ensembl peptide - ENSP00000443099
Ensembl peptide - ENSP00000458219
Ensembl peptide - ENSP00000458553
Ensembl peptide - ENSP00000458809
Ensembl peptide - ENSP00000458918
Ensembl peptide - ENSP00000459003
Ensembl peptide - ENSP00000459079
Ensembl peptide - ENSP00000460213
Ensembl peptide - ENSP00000460565
Ensembl peptide - ENSP00000460721
Ensembl peptide - ENSP00000460823
Ensembl peptide - ENSP00000461215
Ensembl peptide - ENSP00000461284
NCBI entrez gene - 10040     See in Manteia.
OMIM - 604701
RefSeq - NM_001321174
RefSeq - NM_001321173
RefSeq - NM_001321175
RefSeq - NM_001321176
RefSeq - NM_005486
RefSeq - XM_017024002
RefSeq Peptide - NP_001308105
RefSeq Peptide - NP_005477
RefSeq Peptide - NP_001308104
RefSeq Peptide - NP_001308102
RefSeq Peptide - NP_001308103
swissprot - J3KQU4
swissprot - K7EP47
swissprot - I3L0N2
swissprot - O75674
swissprot - I3L1G1
swissprot - I3L1Q1
swissprot - I3L1T2
swissprot - I3L367
swissprot - I3L3T4
swissprot - I3L3M3
swissprot - I3L4G0
swissprot - I3L4I4
swissprot - I3L4N3
swissprot - I3NI44
Ensembl - ENSG00000141198
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TOM1L1ENSGALG00000003011Gallus gallus
 Q923U0ENSMUSG00000020541Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6ZVM7 / TOM1L2 / target of myb1 like 2 membrane trafficking proteinENSG0000017566233
TOM1 / O60784 / target of myb1 membrane trafficking proteinENSG0000010028432
GGA3 / Q9NZ52 / golgi associated, gamma adaptin ear containing, ARF binding protein 3ENSG0000012544722
GGA1 / Q9UJY5 / golgi associated, gamma adaptin ear containing, ARF binding protein 1ENSG0000010008320
GGA2 / Q9UJY4 / golgi associated, gamma adaptin ear containing, ARF binding protein 2ENSG0000010336520


Protein motifs (from Interpro)
Interpro ID Name
 IPR002014  VHS domain
 IPR004152  GAT domain
 IPR008942  ENTH/VHS
 IPR014645  Target of Myb protein 1
 IPR027428  TOM1-like protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IDA
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway NAS
 biological_processGO:0045839 negative regulation of mitotic nuclear division IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome TAS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0030276 clathrin binding IDA
 molecular_functionGO:0030295 protein kinase activator activity IEA
 molecular_functionGO:0043130 ubiquitin binding TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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