ENSG00000100284


Homo sapiens

Features
Gene ID: ENSG00000100284
  
Biological name :TOM1
  
Synonyms : O60784 / target of myb1 membrane trafficking protein / TOM1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q12.3
Gene start: 35299275
Gene end: 35347994
  
Corresponding Affymetrix probe sets: 202807_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000413697
Ensembl peptide - ENSP00000398876
Ensembl peptide - ENSP00000476698
Ensembl peptide - ENSP00000477471
Ensembl peptide - ENSP00000371465
Ensembl peptide - ENSP00000379085
Ensembl peptide - ENSP00000385906
Ensembl peptide - ENSP00000389789
Ensembl peptide - ENSP00000390429
Ensembl peptide - ENSP00000393714
Ensembl peptide - ENSP00000394466
Ensembl peptide - ENSP00000394924
Ensembl peptide - ENSP00000394944
Ensembl peptide - ENSP00000397492
NCBI entrez gene - 10043     See in Manteia.
OMIM - 604700
RefSeq - XM_017028530
RefSeq - NM_001135729
RefSeq - NM_001135730
RefSeq - NM_001135732
RefSeq - NM_005488
RefSeq - XM_011529818
RefSeq - XM_011529820
RefSeq - XM_017028529
RefSeq Peptide - NP_001129201
RefSeq Peptide - NP_001129202
RefSeq Peptide - NP_001129204
RefSeq Peptide - NP_005479
swissprot - B0QY02
swissprot - F8WAW7
swissprot - F8WB30
swissprot - F8WBB0
swissprot - F8WE29
swissprot - H7BYN7
swissprot - V9GYF4
swissprot - Q6UW50
swissprot - V9GZ68
swissprot - B0QY01
swissprot - O60784
Ensembl - ENSG00000100284
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tom1ENSDARG00000104581Danio rerio
 TOM1ENSGALG00000012552Gallus gallus
 Tom1ENSMUSG00000042870Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6ZVM7 / TOM1L2 / target of myb1 like 2 membrane trafficking proteinENSG0000017566264
O75674 / TOM1L1 / target of myb1 like 1 membrane trafficking proteinENSG0000014119831
GGA3 / Q9NZ52 / golgi associated, gamma adaptin ear containing, ARF binding protein 3ENSG0000012544724
GGA1 / Q9UJY5 / golgi associated, gamma adaptin ear containing, ARF binding protein 1ENSG0000010008322
GGA2 / Q9UJY4 / golgi associated, gamma adaptin ear containing, ARF binding protein 2ENSG0000010336520


Protein motifs (from Interpro)
Interpro ID Name
 IPR002014  VHS domain
 IPR004152  GAT domain
 IPR008942  ENTH/VHS
 IPR014645  Target of Myb protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006897 endocytosis NAS
 biological_processGO:0015031 protein transport NAS
 biological_processGO:0016197 endosomal transport TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030276 clathrin binding IDA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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