ENSG00000143578


Homo sapiens

Features
Gene ID: ENSG00000143578
  
Biological name :CREB3L4
  
Synonyms : cAMP responsive element binding protein 3 like 4 / CREB3L4 / Q8TEY5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.3
Gene start: 153967534
Gene end: 153974363
  
Corresponding Affymetrix probe sets: 226455_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402308
Ensembl peptide - ENSP00000271889
Ensembl peptide - ENSP00000357589
Ensembl peptide - ENSP00000357590
Ensembl peptide - ENSP00000357592
Ensembl peptide - ENSP00000357596
Ensembl peptide - ENSP00000391847
NCBI entrez gene - 148327     See in Manteia.
OMIM - 607138
RefSeq - XM_017000372
RefSeq - NM_001255978
RefSeq - NM_001255979
RefSeq - NM_001255980
RefSeq - NM_001255981
RefSeq - NM_130898
RefSeq - XM_006711172
RefSeq Peptide - NP_001242909
RefSeq Peptide - NP_001242910
RefSeq Peptide - NP_570968
RefSeq Peptide - NP_001242907
RefSeq Peptide - NP_001242908
swissprot - Q5T4L2
swissprot - Q8TEY5
swissprot - Q5T4K9
swissprot - Q5T4L1
Ensembl - ENSG00000143578
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9D2A5ENSMUSG00000027938Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q68CJ9 / CREB3L3 / cAMP responsive element binding protein 3 like 3ENSG0000006056637
CREB3 / O43889 / cAMP responsive element binding protein 3ENSG0000010717527
Q96BA8 / CREB3L1 / cAMP responsive element binding protein 3 like 1ENSG0000015761325
Q70SY1 / CREB3L2 / cAMP responsive element binding protein 3 like 2ENSG0000018215825


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR029807  cAMP-responsive element-binding protein 3-like protein 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0035497 cAMP response element binding IEA


Pathways (from Reactome)
Pathway description
CREB3 factors activate genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000140943 MBTPS1 / Q14703 / membrane bound transcription factor peptidase, site 1  / reaction
 ENSG00000012174 MBTPS2 / O43462 / membrane bound transcription factor peptidase, site 2  / reaction






 

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