ENSG00000144644


Homo sapiens

Features
Gene ID: ENSG00000144644
  
Biological name :GADL1
  
Synonyms : GADL1 / glutamate decarboxylase like 1 / Q6ZQY3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p23
Gene start: 30726200
Gene end: 30894765
  
Corresponding Affymetrix probe sets: 1563533_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000282538
Ensembl peptide - ENSP00000427059
NCBI entrez gene - 339896     See in Manteia.
OMIM - 615601
RefSeq - XM_017006297
RefSeq - NM_207359
RefSeq Peptide - NP_997242
swissprot - Q6ZQY3
Ensembl - ENSG00000144644
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GADL1ENSGALG00000011447Gallus gallus
 Gadl1ENSMUSG00000056880Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CSAD / Q9Y600 / cysteine sulfinic acid decarboxylaseENSG0000013963156
GAD1 / Q99259 / glutamate decarboxylase 1ENSG0000012868348
GAD2 / Q05329 / glutamate decarboxylase 2ENSG0000013675046
HDC / P19113 / histidine decarboxylaseENSG0000014028722
DDC / P20711 / dopa decarboxylaseENSG0000013243720


Protein motifs (from Interpro)
Interpro ID Name
 IPR002129  Pyridoxal phosphate-dependent decarboxylase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR021115  Pyridoxal-phosphate binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008652 cellular amino acid biosynthetic process TAS
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004068 aspartate 1-decarboxylase activity IEA
 molecular_functionGO:0004782 sulfinoalanine decarboxylase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity TAS
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Degradation of cysteine and homocysteine
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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