ENSG00000146122


Homo sapiens

Features
Gene ID: ENSG00000146122
  
Biological name :DAAM2
  
Synonyms : DAAM2 / dishevelled associated activator of morphogenesis 2 / Q86T65
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.2
Gene start: 39792298
Gene end: 39904877
  
Corresponding Affymetrix probe sets: 212793_at (Human Genome U133 Plus 2.0 Array)   241442_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000437808
Ensembl peptide - ENSP00000384637
Ensembl peptide - ENSP00000488196
Ensembl peptide - ENSP00000488831
Ensembl peptide - ENSP00000274867
Ensembl peptide - ENSP00000381876
NCBI entrez gene - 23500     See in Manteia.
OMIM - 606627
RefSeq - XM_017010630
RefSeq - XM_006715039
RefSeq - XM_006715040
RefSeq - XM_006715042
RefSeq - XM_006715043
RefSeq - XM_006715045
RefSeq - XM_006715046
RefSeq - NM_001201427
RefSeq - NM_015345
RefSeq Peptide - NP_001188356
RefSeq Peptide - NP_056160
swissprot - A0A0J9YYF7
swissprot - F2Z2Q2
swissprot - Q86T65
swissprot - A0A0J9YX09
Ensembl - ENSG00000146122
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 daam2ENSDARG00000028393Danio rerio
 DAAM2ENSGALG00000010055Gallus gallus
 Daam2ENSMUSG00000040260Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DAAM1 / Q9Y4D1 / dishevelled associated activator of morphogenesis 1ENSG0000010059269
DIAPH1 / O60610 / diaphanous related formin 1ENSG0000013150427
DIAPH3 / Q9NSV4 / diaphanous related formin 3ENSG0000013973426
FMNL1 / O95466 / formin like 1ENSG0000018492225
DIAPH2 / O60879 / diaphanous related formin 2ENSG0000014720225
FMNL2 / Q96PY5 / formin like 2ENSG0000015782724
FMNL3 / Q8IVF7 / formin like 3ENSG0000016179123
INF2 / Q27J81 / inverted formin, FH2 and WH2 domain containingENSG0000020348523
FHDC1 / Q9C0D6 / FH2 domain containing 1ENSG0000013746014


Protein motifs (from Interpro)
Interpro ID Name
 IPR010472  Formin, FH3 domain
 IPR010473  Formin, GTPase-binding domain
 IPR011989  Armadillo-like helical
 IPR014767  Diaphanous autoregulatory (DAD) domain
 IPR014768  Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
 IPR015425  Formin, FH2 domain
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007368 determination of left/right symmetry IEA
 biological_processGO:0016043 cellular component organization IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0021516 dorsal spinal cord development ISS
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0048715 negative regulation of oligodendrocyte differentiation ISS
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway ISS
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway ISS
 biological_processGO:2000050 regulation of non-canonical Wnt signaling pathway ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr