ENSG00000147596


Homo sapiens

Features
Gene ID: ENSG00000147596
  
Biological name :PRDM14
  
Synonyms : PRDM14 / PR/SET domain 14 / Q9GZV8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q13.3
Gene start: 70051651
Gene end: 70071693
  
Corresponding Affymetrix probe sets: 220714_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000276594
Ensembl peptide - ENSP00000408653
NCBI entrez gene - 63978     See in Manteia.
OMIM - 611781
RefSeq - NM_024504
RefSeq - XM_011517572
RefSeq Peptide - NP_078780
swissprot - C9JMM8
swissprot - Q9GZV8
Ensembl - ENSG00000147596
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 E9Q3T6ENSMUSG00000042414Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRDM6 / Q9NQX0 / PR/SET domain 6ENSG0000006145523
PRDM4 / Q9UKN5 / PR/SET domain 4ENSG0000011085119
PRDM12 / Q9H4Q4 / PR/SET domain 12ENSG0000013071118
RTCB / Q9Y3I0 / RNA 2,3-cyclic phosphate and 5-OH ligaseENSG000001002208


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0001708 cell fate specification IEA
 biological_processGO:0001827 inner cell mass cell fate commitment IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007281 germ cell development IEA
 biological_processGO:0007566 embryo implantation IEA
 biological_processGO:0009566 fertilization IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0030718 germ-line stem cell population maintenance IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034972 histone H3-R26 methylation IEA
 biological_processGO:0035019 somatic stem cell population maintenance TAS
 biological_processGO:0040029 regulation of gene expression, epigenetic IEA
 biological_processGO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0044030 regulation of DNA methylation IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0060817 inactivation of paternal X chromosome IEA
 biological_processGO:1902093 positive regulation of flagellated sperm motility IEA
 biological_processGO:1902459 positive regulation of stem cell population maintenance IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031490 chromatin DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Transcriptional regulation of pluripotent stem cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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