ENSG00000100220


Homo sapiens

Features
Gene ID: ENSG00000100220
  
Biological name :RTCB
  
Synonyms : Q9Y3I0 / RNA 2,3-cyclic phosphate and 5-OH ligase / RTCB
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q12.3
Gene start: 32387582
Gene end: 32412255
  
Corresponding Affymetrix probe sets: 200042_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000216038
NCBI entrez gene - 51493     See in Manteia.
OMIM - 613901
RefSeq - NM_014306
RefSeq Peptide - NP_055121
swissprot - Q9Y3I0
Ensembl - ENSG00000100220
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prdm4ENSDARG00000017366Danio rerio
 RtcbENSMUSG00000001783Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRDM4 / Q9UKN5 / PR/SET domain 4ENSG0000011085111
PRDM6 / Q9NQX0 / PR/SET domain 6ENSG000000614559
PRDM14 / Q9GZV8 / PR/SET domain 14ENSG000001475969
PRDM12 / Q9H4Q4 / PR/SET domain 12ENSG000001307116


Protein motifs (from Interpro)
Interpro ID Name
 IPR001233  tRNA-splicing ligase, RtcB
 IPR027513  tRNA-splicing ligase RtcB homologue, eukaryotic
 IPR036025  tRNA-splicing ligase RtcB-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation TAS
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0008033 tRNA processing IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0072669 tRNA-splicing ligase complex IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003972 RNA ligase (ATP) activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008452 RNA ligase activity IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0017166 vinculin binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
tRNA processing in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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