ENSG00000148835


Homo sapiens

Features
Gene ID: ENSG00000148835
  
Biological name :TAF5
  
Synonyms : Q15542 / TAF5 / TATA-box binding protein associated factor 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q24.33
Gene start: 103367967
Gene end: 103389065
  
Corresponding Affymetrix probe sets: 1553528_a_at (Human Genome U133 Plus 2.0 Array)   210053_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358854
NCBI entrez gene - 6877     See in Manteia.
OMIM - 601787
RefSeq - NM_139052
RefSeq - NM_006951
RefSeq Peptide - NP_008882
RefSeq Peptide - NP_620640
swissprot - Q15542
Ensembl - ENSG00000148835
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taf5ENSDARG00000018325Danio rerio
 TAF5ENSGALG00000008241Gallus gallus
 Taf5ENSMUSG00000025049Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TAF5L / O75529 / TATA-box binding protein associated factor 5 likeENSG0000013580129
Q8NAA4 / ATG16L2 / autophagy related 16 like 2ENSG0000016801013
Q676U5 / ATG16L1 / autophagy related 16 like 1ENSG0000008597811
WDR83 / Q9BRX9 / WD repeat domain 83ENSG000001231548


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR006594  LIS1 homology motif
 IPR007582  TFIID subunit TAF5, NTD2 domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily
 IPR037264  TFIID subunit TAF5, NTD2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IC
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006352 DNA-templated transcription, initiation IDA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0042795 snRNA transcription by RNA polymerase II TAS
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005669 transcription factor TFIID complex IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0033276 transcription factor TFTC complex IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IMP
 molecular_functionGO:0004402 histone acetyltransferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046983 protein dimerization activity IDA


Pathways (from Reactome)
Pathway description
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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