ENSG00000123154


Homo sapiens

Features
Gene ID: ENSG00000123154
  
Biological name :WDR83
  
Synonyms : Q9BRX9 / WDR83 / WD repeat domain 83
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.13
Gene start: 12666800
Gene end: 12675832
  
Corresponding Affymetrix probe sets: 224434_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448331
Ensembl peptide - ENSP00000448722
Ensembl peptide - ENSP00000449257
Ensembl peptide - ENSP00000450416
Ensembl peptide - ENSP00000396530
Ensembl peptide - ENSP00000402653
NCBI entrez gene - 84292     See in Manteia.
OMIM - 616850
RefSeq - NM_032332
RefSeq - NM_001099737
RefSeq Peptide - NP_001093207
RefSeq Peptide - NP_115708
swissprot - Q9BRX9
swissprot - F8VSE4
swissprot - G3V221
swissprot - H0YIE8
swissprot - H7C0S9
Ensembl - ENSG00000123154
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wdr83ENSDARG00000041600Danio rerio
 Wdr83ENSMUSG00000005150Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8NAA4 / ATG16L2 / autophagy related 16 like 2ENSG0000016801023
Q676U5 / ATG16L1 / autophagy related 16 like 1ENSG0000008597822
TAF5 / Q15542 / TATA-box binding protein associated factor 5ENSG0000014883520
TAF5L / O75529 / TATA-box binding protein associated factor 5 likeENSG0000013580119


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000375 RNA splicing, via transesterification reactions IDA
 biological_processGO:0000398 mRNA splicing, via spliceosome IDA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
MAP2K and MAPK activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100030 MAPK1 / P28482 / mitogen-activated protein kinase 1  / complex / reaction
 ENSG00000109270 Q9UHA4 / LAMTOR3 / late endosomal/lysosomal adaptor, MAPK and MTOR activator 3  / complex
 ENSG00000132155 RAF1 / P04049 / Raf-1 proto-oncogene, serine/threonine kinase  / complex / reaction
 ENSG00000126934 MAP2K2 / P36507 / mitogen-activated protein kinase kinase 2  / complex / reaction
 ENSG00000102882 MAPK3 / P27361 / mitogen-activated protein kinase 3  / complex / reaction
 ENSG00000169032 MAP2K1 / Q02750 / mitogen-activated protein kinase kinase 1  / reaction / complex
 ENSG00000157764 BRAF / P15056 / B-Raf proto-oncogene, serine/threonine kinase  / reaction / complex
 ENSG00000116586 Q9Y2Q5 / LAMTOR2 / late endosomal/lysosomal adaptor, MAPK and MTOR activator 2  / complex






 

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