ENSG00000150051


Homo sapiens

Features
Gene ID: ENSG00000150051
  
Biological name :MKX
  
Synonyms : MKX / mohawk homeobox / Q8IYA7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: p12.1
Gene start: 27672875
Gene end: 27746060
  
Corresponding Affymetrix probe sets: 236014_at (Human Genome U133 Plus 2.0 Array)   239468_at (Human Genome U133 Plus 2.0 Array)   241902_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364946
Ensembl peptide - ENSP00000400896
Ensembl peptide - ENSP00000452751
Ensembl peptide - ENSP00000453746
NCBI entrez gene - 283078     See in Manteia.
OMIM - 601332
RefSeq - XM_017016108
RefSeq - NM_001242702
RefSeq - NM_173576
RefSeq - XM_017016105
RefSeq - XM_017016106
RefSeq - XM_017016107
RefSeq Peptide - NP_001229631
RefSeq Peptide - NP_775847
swissprot - H0YMU2
swissprot - Q8IYA7
swissprot - H0YKC7
Ensembl - ENSG00000150051
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mkxaENSDARG00000075450Danio rerio
 mkxbENSDARG00000114182Danio rerio
 MKXENSGALG00000007426Gallus gallus
 MkxENSMUSG00000061013Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IRX5 / P78411 / iroquois homeobox 5ENSG0000017684224
IRX4 / P78413 / iroquois homeobox 4ENSG0000011343023
IRX3 / P78415 / iroquois homeobox 3ENSG0000017750823
IRX6 / P78412 / iroquois homeobox 6ENSG0000015938723
IRX2 / Q9BZI1 / iroquois homeobox 2ENSG0000017056122
IRX1 / P78414 / iroquois homeobox 1ENSG0000017054920


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007517 muscle organ development ISS
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr