ENSDARG00000075450


Danio rerio

Features
Gene ID: ENSDARG00000075450
  
Biological name :mkxa
  
Synonyms : mkxa / mohawk homeobox a
  
Possible biological names infered from orthology : MKX / mohawk homeobox / Q8IYA7
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 22961894
Gene end: 23009312
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000102484
NCBI entrez gene - 799136     See in Manteia.
RefSeq - NM_001098733
RefSeq Peptide - NP_001092203
swissprot - A9UGK1
ZFIN ID - ZDB-GENE-080513-1
Ensembl - ENSDARG00000075450
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MKXENSGALG00000007426Gallus gallus
 MKXENSG00000150051Homo sapiens
 MkxENSMUSG00000061013Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mkxb / mohawk homeobox b / MKX* / Q8IYA7* / mohawk homeobox*ENSDARG0000011418266
irx4a / iroquois homeobox 4a / IRX4* / P78413* / Q9QY61* / iroquois homeobox 4* / Iroquois-class homeodomain protein IRX-4 *ENSDARG0000003564822
irx6a / iroquois homeobox 6a / IRX6* / P78412* / Q9ER75* / iroquois homeobox 6* / Iroquois-class homeodomain protein IRX-6 *ENSDARG0000003442021
irx3a / iroquois homeobox 3a / IRX3* / P78415* / P81067* / iroquois homeobox 3* / Iroquois-class homeodomain protein IRX-3 *ENSDARG0000010107620
irx1a / iroquois homeobox 1a / IRX1* / P78414* / iroquois homeobox 1*ENSDARG0000010183120
irx2a / iroquois homeobox 2a / IRX2* / P81066* / Q9BZI1* / iroquois homeobox 2* / Iroquois-class homeodomain protein IRX-2 *ENSDARG0000000178518
irx5a / iroquois homeobox 5a / IRX5* / P78411* / Q9JKQ4* / iroquois homeobox 5* / Iroquois-class homeodomain protein IRX-5 *ENSDARG0000003404318
irx4b / iroquois homeobox 4b / IRX4* / P78413* / Q9QY61* / iroquois homeobox 4* / Iroquois-class homeodomain protein IRX-4 *ENSDARG0000003605118
irx3b / iroquois homeobox 3b / IRX3* / P78415* / iroquois homeobox 3*ENSDARG0000003113817
irx1b / iroquois homeobox 1bENSDARG0000005659417
irx5b / iroquois homeobox 5b / IRX5* / P78411* / Q9JKQ4* / iroquois homeobox 5* / Iroquois-class homeodomain protein IRX-5 *ENSDARG0000007407015
irx7 / iroquois homeobox 7ENSDARG0000000260114


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045445 myoblast differentiation IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IGI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain malformed , abnormal
Show

 ZFA:0000045 neural crest neural crest physical object quality , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000511 extraocular musculature extraocular musculature decreased amount , abnormal
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 ZFA:0001114 head head flat , abnormal
head decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved dorsal , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased size , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton malformed , abnormal
Show

 ZFA:0001261 ventricular system ventricular system malformed , abnormal
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 ZFA:0001307 pharyngeal musculature pharyngeal musculature decreased amount , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage decreased size , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
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 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage physical object quality , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage malformed , abnormal
ceratobranchial cartilage decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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