ENSDARG00000031138


Danio rerio

Features
Gene ID: ENSDARG00000031138
  
Biological name :irx3b
  
Synonyms : iroquois homeobox 3b / irx3b
  
Possible biological names infered from orthology : Iroquois-class homeodomain protein IRX-3 / iroquois homeobox 3 / IRX3 / P78415 / P81067
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 36488164
Gene end: 36492779
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000042270
swissprot - F1Q7T5
ZFIN ID - ZDB-GENE-030131-525
Ensembl - ENSDARG00000031138
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IRX3ENSGALG00000042045Gallus gallus
 IRX3ENSG00000177508Homo sapiens
 Irx3ENSMUSG00000031734Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
irx3a / iroquois homeobox 3a / IRX3* / P78415* / P81067* / iroquois homeobox 3* / Iroquois-class homeodomain protein IRX-3 *ENSDARG0000010107655
irx1a / iroquois homeobox 1a / IRX1* / P78414* / iroquois homeobox 1*ENSDARG0000010183143
irx1b / iroquois homeobox 1bENSDARG0000005659440
irx4a / iroquois homeobox 4a / IRX4* / P78413* / Q9QY61* / iroquois homeobox 4* / Iroquois-class homeodomain protein IRX-4 *ENSDARG0000003564836
irx5a / iroquois homeobox 5a / IRX5* / P78411* / Q9JKQ4* / iroquois homeobox 5* / Iroquois-class homeodomain protein IRX-5 *ENSDARG0000003404334
irx5b / iroquois homeobox 5b / IRX5* / P78411* / Q9JKQ4* / iroquois homeobox 5* / Iroquois-class homeodomain protein IRX-5 *ENSDARG0000007407034
irx2a / iroquois homeobox 2a / IRX2* / P81066* / Q9BZI1* / iroquois homeobox 2* / Iroquois-class homeodomain protein IRX-2 *ENSDARG0000000178534
irx6a / iroquois homeobox 6a / IRX6* / P78412* / Q9ER75* / iroquois homeobox 6* / Iroquois-class homeodomain protein IRX-6 *ENSDARG0000003442034
irx4b / iroquois homeobox 4b / IRX4* / P78413* / Q9QY61* / iroquois homeobox 4* / Iroquois-class homeodomain protein IRX-4 *ENSDARG0000003605131
irx7 / iroquois homeobox 7ENSDARG0000000260129
mkxa / mohawk homeobox a / MKX* / Q8IYA7* / mohawk homeobox*ENSDARG0000007545018
mkxb / mohawk homeobox b / MKX* / Q8IYA7* / mohawk homeobox*ENSDARG0000011418217


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003893  Iroquois-class homeodomain protein
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0035778 pronephric nephron tubule epithelial cell differentiation IMP
 biological_processGO:0039023 pronephric duct morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000150 pronephric duct pronephric duct proximal region increased length , abnormal
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 ZFA:0001622 pronephric distal early tubule pronephric distal early tubule poorly differentiated , abnormal
pronephric distal early tubule absent , abnormal
Show

 ZFA:0001624 pronephric distal late tubule pronephric distal late tubule increased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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