ENSDARG00000101076


Danio rerio

Features
Gene ID: ENSDARG00000101076
  
Biological name :irx3a
  
Synonyms : iroquois homeobox 3a / irx3a
  
Possible biological names infered from orthology : Iroquois-class homeodomain protein IRX-3 / iroquois homeobox 3 / IRX3 / P78415 / P81067
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 36035432
Gene end: 36048078
  
Corresponding Affymetrix probe sets: Dr.8282.2.S1_a_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000143874
Ensembl peptide - ENSDARP00000139882
NCBI entrez gene - 30520     See in Manteia.
RefSeq - NM_001320125
RefSeq Peptide - NP_001307054
swissprot - A0A286Y9M4
swissprot - Q90Z68
ZFIN ID - ZDB-GENE-991119-5
Ensembl - ENSDARG00000101076
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IRX3ENSGALG00000042045Gallus gallus
 IRX3ENSG00000177508Homo sapiens
 Irx3ENSMUSG00000031734Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
irx3b / iroquois homeobox 3b / IRX3* / P78415* / iroquois homeobox 3*ENSDARG0000003113842
irx1a / iroquois homeobox 1a / IRX1* / P78414* / iroquois homeobox 1*ENSDARG0000010183139
irx1b / iroquois homeobox 1bENSDARG0000005659433
irx6a / iroquois homeobox 6a / IRX6* / P78412* / Q9ER75* / iroquois homeobox 6* / Iroquois-class homeodomain protein IRX-6 *ENSDARG0000003442029
irx5a / iroquois homeobox 5a / IRX5* / P78411* / Q9JKQ4* / iroquois homeobox 5* / Iroquois-class homeodomain protein IRX-5 *ENSDARG0000003404329
irx4a / iroquois homeobox 4a / IRX4* / P78413* / Q9QY61* / iroquois homeobox 4* / Iroquois-class homeodomain protein IRX-4 *ENSDARG0000003564829
irx4b / iroquois homeobox 4b / IRX4* / P78413* / Q9QY61* / iroquois homeobox 4* / Iroquois-class homeodomain protein IRX-4 *ENSDARG0000003605127
irx2a / iroquois homeobox 2a / IRX2* / P81066* / Q9BZI1* / iroquois homeobox 2* / Iroquois-class homeodomain protein IRX-2 *ENSDARG0000000178526
irx5b / iroquois homeobox 5b / IRX5* / P78411* / Q9JKQ4* / iroquois homeobox 5* / Iroquois-class homeodomain protein IRX-5 *ENSDARG0000007407026
irx7 / iroquois homeobox 7ENSDARG0000000260123
mkxa / mohawk homeobox a / MKX* / Q8IYA7* / mohawk homeobox*ENSDARG0000007545015
mkxb / mohawk homeobox b / MKX* / Q8IYA7* / mohawk homeobox*ENSDARG0000011418214


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003893  Iroquois-class homeodomain protein
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0031018 endocrine pancreas development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001390 pancreatic bud pancreatic bud has fewer parts of type pancreatic B cell , abnormal
pancreatic bud has fewer parts of type pancreatic A cell , abnormal
pancreatic bud has extra parts of type pancreatic epsilon cell , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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